Thigh sarcopenia and hypoalbuminemia predict impaired overall survival after infrainguinal revascularization in patients with critical limb ischemia

Autor: Koichi Morisaki, Sho Yamashita, Ken Nakayama, Keiji Yoshiya, Kentaro Inoue, Yutaka Matsubara, Shun Kurose, Masaki Mori, Shinichiro Yoshino, Tadashi Furuyama
Rok vydání: 2020
Předmět:
Male
Sarcopenia
medicine.medical_specialty
Time Factors
Critical Illness
medicine.medical_treatment
Serum Albumin
Human
030204 cardiovascular system & hematology
Thigh
Revascularization
Peripheral Arterial Disease
03 medical and health sciences
0302 clinical medicine
Ischemia
Risk Factors
Internal medicine
medicine
Overall survival
Humans
Radiology
Nuclear Medicine and imaging
In patient
Hypoalbuminemia
Muscle
Skeletal
Aged
Retrospective Studies
Aged
80 and over
business.industry
General Medicine
Critical limb ischemia
Middle Aged
musculoskeletal system
medicine.disease
body regions
Treatment Outcome
medicine.anatomical_structure
Body Composition
Cardiology
Female
Surgery
medicine.symptom
Tomography
X-Ray Computed
Cardiology and Cardiovascular Medicine
business
Vascular Surgical Procedures
Biomarkers
030217 neurology & neurosurgery
Zdroj: Vascular. 28:542-547
ISSN: 1708-539X
1708-5381
DOI: 10.1177/1708538120913745
Popis: Objective This study was performed to determine whether thigh sarcopenia can serve as a clinically relevant predictor of postoperative complications and overall survival after revascularization in patients with critical limb ischemia. Methods Patients who underwent preoperative computed tomography followed by infrainguinal revascularization from 2006 to 2015 were retrospectively analyzed. An axial computed tomography image was obtained at the midpoint of a line extending from the superior border of the patella to the greater trochanter of the femur. The thigh muscle area and bone area were measured. Thigh sarcopenia was defined as thigh muscle area/thigh bone area of Results We included 117 patients with critical limb ischemia who underwent infrainguinal revascularization. The overall survival rates at two years were 86.5% and 55.1% in the thigh sarcopenia (−) and (+) groups, respectively ( p Conclusion Thigh sarcopenia is a risk factor for two-year overall survival in patients with critical limb ischemia after infrainguinal revascularization.
Databáze: OpenAIRE
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