Orchiectomy versus Oestrogen in the Treatment of Advanced Prostatic Cancer
| Autor: | Reijo Haapiainen, Sakari Rannikko, M. Saarialho, M. Ala-Opas, J. Permi, J. K. Viitanen, Harri Juusela, O. Alfthan, Mirja Ruutu, Hansson E |
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| Rok vydání: | 1991 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Combination therapy medicine.drug_class Urology medicine.medical_treatment Administration Oral Ethinyl Estradiol Injections Intramuscular Estradiol Congeners Prostate Oral administration medicine Humans Orchiectomy Neoplasm Metastasis Aged Gynecology Chemotherapy Estradiol business.industry Mortality rate Prostatic Neoplasms Cancer Prognosis medicine.disease medicine.anatomical_structure Estrogen Female business |
| Zdroj: | British Journal of Urology. 67:184-187 |
| ISSN: | 1464-410X 0007-1331 |
| Popis: | The primary clinical efficacy of orchiectomy and the combination therapy of intramuscular polyoestradiol phosphate 80 mg monthly and oral ethinyl oestradiol 0.15 mg daily was evaluated by progression and cancer mortality rates in a series of 277 prostatic cancer patients representing part of the Finnprostate study. After a follow-up of 5 years there was a significant difference between the groups in terms of progression rate and prostatic cancer deaths. The oestrogen combination was more effective in delaying progression of the disease. The overall mortality rate was similar in both groups. About one-third of the patients were alive after 5 years. |
| Databáze: | OpenAIRE |
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