Electron microscopy of the tana poxvirus
Autor: | Carlos Espana, Mary Ann Brayton, Boris H. Ruebner |
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Rok vydání: | 1971 |
Předmět: |
viruses
Clinical Biochemistry Biology Kidney Virus Pathology and Forensic Medicine Serology law.invention Myelin Tana virus Tissue culture Cytopathogenic Effect Viral law Culture Techniques Tumor Virus medicine Animals Nucleoid Molecular Biology Yaba monkey tumor virus Poxviridae Monkey Diseases Haplorhini Virology Microscopy Electron medicine.anatomical_structure Electron microscope |
Zdroj: | Experimental and Molecular Pathology. 15:34-42 |
ISSN: | 0014-4800 |
DOI: | 10.1016/0014-4800(71)90017-7 |
Popis: | The fine structure of Tana virus, a poxvirus originally isolated from children in Kenya, has been studied by electron microscopy of infected rhesus embryonic monkey tissue cultures. The intracytoplasmic maturation of the virus has been analyzed and compared with that seen in Yaba-like disease (Y.L.D.), an epidermal pox disease of monkeys. Two types of virus factories have been distinguished, one of which appears to be responsible for formation of nucleoids, the other for virus membranes. Honeycombed crystals, cylindrical tubules, mitochondria in pairs or triplets, and myelin figures were also observed. The nuclei showed areas of decreased electron opacity. The development of Tana virus was identical with that of Y.L.D. virus. These findings are consistent with the hypothesis, based on serologic studies, that Tana poxvirus is identical with Y.L.D. virus but differs from a similar monkey poxvirus, the Yaba tumor virus. |
Databáze: | OpenAIRE |
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