| Popis: |
Among the radioisotopes which have therapeutic value is radioactive gold, AU198. It has a half-life of 2.8 days and decays with both beta and gamma emissions. One peculiar advantage of this element is that it can be prepared as a colloid which is chemically stable and relatively inert biologically. Dr. Paul Hahn, of Meharry Medical College, has introduced the use of this isotope for direct injection of tumors and intravenous administration (1, 2, 3). Its value as a means of irradiating body cavities for the control of fluid accumulation is the subject of the present discussion. This use for the isotope was first suggested by J. Muller (4), of Switzerland. During the last two years our group at the Oak Ridge Institute has been carrying on a program of experimental treatment with radioactive colloidal gold. The present discussion is based largely upon material which has already appeared in other publications (5–8). We have injected the isotope into pleural and peritoneal spaces of patients with effusions ca... |
