IS6110-based Differentiation of Mycobacterium tuberculosis Strains
| Autor: | Małgorzata Ziółkiewicz, Anna Sajduda, Arkadiusz Wojtasik, Jaroslaw Dziadek, Anna Zaczek |
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| Rok vydání: | 2013 |
| Předmět: |
Microbiology (medical)
Genetic diversity Tuberculosis Base Sequence biology Gene Expression Regulation Bacterial Mycobacterium tuberculosis General Medicine biology.organism_classification medicine.disease Applied Microbiology and Biotechnology Microbiology Is6110 rflp law.invention Discriminatory power law Polymorphism (computer science) medicine Cluster Analysis Restriction fragment length polymorphism Transcriptome Polymorphism Restriction Fragment Length Polymerase chain reaction |
| Zdroj: | Polish Journal of Microbiology. 62:201-204 |
| ISSN: | 2544-4646 1733-1331 |
| DOI: | 10.33073/pjm-2013-026 |
| Popis: | In this study, 62 Mycobacterium tuberculosis strains were characterized by fast ligation-mediated PCR (FLiP) and, previously performed, IS6110 restriction fragment length polymorphism (RFLP). FLiP proved a reproducible and specific method for differentiation between M. tuberculosis strains. The discriminatory power of FLiP was close to that of the reference IS6110 RFLP suggesting its usefulness in studying the genetic diversity of M. tuberculosis strains. |
| Databáze: | OpenAIRE |
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