Histological comparison of three apatitic bone substitutes with different carbonate contents in alveolar bone defects in a beagle mandible with simultaneous implant installation
| Autor: | Naito Kurio, Kunio Ishikawa, Takamitsu Mano, Naoyuki Fukuda, Kazuya Akita, Kumiko Kamada, Youji Miyamoto |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Materials science medicine.medical_treatment Biomedical Engineering Carbonates Dentistry 02 engineering and technology Mandible Beagle osteoconductivity Apatite Biomaterials 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Dogs Implants Experimental Apatites Alveolar ridge medicine carbonate apatite Animals Dental implant Dental alveolus business.industry hydroxyapatite 030206 dentistry bone substitute 021001 nanoscience & nanotechnology Mandibular Injuries chemistry visual_art Bone Substitutes visual_art.visual_art_medium Carbonate Implant 0210 nano-technology business |
| Zdroj: | Journal of biomedical materials research. Part B, Applied biomaterialsREFERENCES. 108(4) |
| ISSN: | 1552-4981 |
| Popis: | Since bone apatite is a carbonate apatite containing carbonate in an apatitic structure, carbonate content may be one of the factors governing the osteoconductivity of apatitic bone substitutes. The aim of this study was to evaluate the effects of carbonate content on the osteoconductivity of apatitic bone substitutes using three commercially available bone substitutes for the reconstruction of alveolar bone defects of a beagle mandible with simultaneous dental implant installation. NEOBONE®, Bio-Oss®, and Cytrans® that contain 0.1 mass%, 5.5 mass%, and 12.0 mass% of carbonate, respectively, were used in this study. The amount of newly formed bone in the upper portion of the alveolar bone defect of the beagle’s mandible was 0.7%, 6.6%, and 39.4% at 4 weeks after surgery and 4.7%, 39.5% and 75.2% at 12 weeks after surgery for NEOBONE®, Bio-Oss®, and Cytrans®, respectively. The results indicate that bone-to-implant contact ratio was the largest for Cytrans®. Additionally, the continuity of the alveolar ridge was restored in the case of Cytrans®, whereas the continuity of the alveolar ridge was not sufficient when using NEOBONE® and Bio-Oss®. Both Cytrans® and Bio-Oss® that has a relatively larger carbonate content in their apatitic structure was resorbed with time. We concluded that carbonate content is one of important factors governing the osteoconductivity of apatitic bone substitutes. |
| Databáze: | OpenAIRE |
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