Ability of non-cyclic oligosaccharides to form molecular complexes and its use for chiral separation by capillary zone electrophoresis
| Autor: | Kazumi Horiguchi, Kenji Minami, Koji Kano, Taizo Ishimura, Masahito Kodera |
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| Rok vydání: | 1995 |
| Předmět: |
Electrophoresis
Molecular Sequence Data Oligosaccharides Stereoisomerism Naphthalenes Biochemistry Analytical Chemistry Hydrophobic effect Capillary electrophoresis Carbohydrate Conformation chemistry.chemical_classification Chromatography Chemistry Hydrogen bond Hydrolysis Spectrum Analysis Organic Chemistry Enantioselective synthesis Esters Hydrogen Bonding General Medicine Dicarboxylic acid Carbohydrate Sequence Carbohydrate conformation Enantiomer |
| Zdroj: | Journal of chromatography. A. 694(1) |
| ISSN: | 0021-9673 |
| Popis: | The binding constants (K) for complexation of the phenyl acetates with linear alpha-1,4-linked dextrins have been determined from the kinetics of the hydrolyses of the esters. The K value tends to increase with increasing the number of the glucopyranose units, suggesting hydrophobic interaction as a binding force. The weak ability of the linear dextrins to form the molecular complexes makes it possible to separate the enantiomers of binaphthyl derivatives such as 1,1'-binaphthyl-2,2'-dicarboxylic acid, 1,1'-binaphthyl-2,2'-diyl hydrogenphosphate and 2,2'-dihydroxy-1,1'-binaphthyl-3,3'-dicarboxylic acid in their anionic forms. Hydrogen bonding as well as hydrophobic interaction is suggested as an essential force for enantioselective complexation between saccharide and anionic binaphthyl. |
| Databáze: | OpenAIRE |
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