Cryptococcal Meningitis With Acute Psychotic Confusion in a Sarcoid Patient

Autor: Jean-Louis Goeb, Virginie Leon, Géraldine Kechid
Přispěvatelé: Laboratoire de Neurosciences Fonctionnelles et Pathologies (LNFP), Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS), Laboratoire des colloïdes, verres et nanomatériaux (LCVN), Université Montpellier 2 - Sciences et Techniques (UM2)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche sur la Matière Divisée (CRMD), Centre National de la Recherche Scientifique (CNRS)-Université d'Orléans (UO), Intense Pulsed Neutron Source (IPNS), Argonne National Laboratory [Lemont] (ANL)-University of Chicago
Jazyk: angličtina
Rok vydání: 2007
Předmět:
Zdroj: The Primary Care Companion to the Journal Clinical Psychiatry
The Primary Care Companion to the Journal Clinical Psychiatry, 2007, 9 (5), pp.393-4. ⟨10.1016/S1053-8119(03)00408-7⟩
DOI: 10.1016/S1053-8119(03)00408-7⟩
Popis: International audience; The brain plays a central role in sexual motivation. To identify cerebral areas whose activation was correlated with sexual desire, eight healthy male volunteers were studied with functional magnetic resonance imaging (fMRI). Visual stimuli were sexually stimulating photographs (S condition) and emotionally neutral photographs (N condition). Subjective responses pertaining to sexual desire were recorded after each condition. To image the entire brain, separate runs focused on the upper and the lower parts of the brain. Statistical Parametric Mapping was used for data analysis. Subjective ratings confirmed that sexual pictures effectively induced sexual arousal. In the S condition compared to the N condition, a group analysis conducted on the upper part of the brain demonstrated an increased signal in the parietal lobes (superior parietal lobules, left intraparietal sulcus, left inferior parietal lobule, and right postcentral gyrus), the right parietooccipital sulcus, the left superior occipital gyrus, and the precentral gyri. In addition, a decreased signal was recorded in the right posterior cingulate gyrus and the left precuneus. In individual analyses conducted on the lower part of the brain, an increased signal was found in the right and/or left middle occipital gyrus in seven subjects, and in the right and/or left fusiform gyrus in six subjects. In conclusion, fMRI allows to identify brain responses to visual sexual stimuli. Among activated regions in the S condition, parietal areas are known to be involved in attentional processes directed toward motivationally relevant stimuli, while frontal premotor areas have been implicated in motor preparation and motor imagery. Further work is needed to identify those specific features of the neural responses that distinguish sexual desire from other emotional and motivational states.
Databáze: OpenAIRE