Pelviometry in the normal and the partially obstructed porcine kidney: recordings before and three weeks after application of ureteral obstruction

Autor: Niels Harving, Jens Christian Djurhuus, Peer Christiansen, F. Taagehøj Jensen, Jens Tølbøll Mortensen
Rok vydání: 1988
Předmět:
Zdroj: The Journal of urology. 140(4)
ISSN: 0022-5347
Popis: In 11 pigs a standardized proximal ureteric obstruction was applied. The effect of the obstruction was examined three weeks later. In both the normal and the obstructed systems the pressure-volume relationship was exponential. Mean pelvic capacity increased from 6.5 ml. to 44.1 ml. (p less than 0.002). Mean intrapelvic baseline pressure increased from 10.0 to 16.8 cm. H2O (p less than 0.02), and this parameter correlated positively to volume (rS = 0.79 - p less than 0.05). There was a slight decrease in the relative function of the obstructed kidney on renography (from 49% to 39% of the total renal function), but this was not significant. The decrease in function was correlated to the increase in capacity (rS = -0.69 - p less than 0.05). In this series renal deterioration occurred in the hydronephrotic kidneys, and at least in this model of acute ureteral obstruction there was no support for the theory that hydronephrotic transformation is a compensatory mechanism which protects the kidney when the upper urinary tract is obstructed.
Databáze: OpenAIRE