IMAGING OF HEPATIC TRANSPLANTATION

Autor: H V Nghiem
Rok vydání: 1998
Předmět:
Zdroj: Radiologic Clinics of North America. 36:429-443
ISSN: 0033-8389
DOI: 10.1016/s0033-8389(05)70033-6
Popis: Liver transplantation is indicated for patients with severe acute or chronic liver failure for which no other therapy is available. Acute liver failure has several causes including viral hepatitis (hepatitis A, B, C, D, or E); hepatitis induced by drugs (acetaminophen, isoniazid, or other medications); ingestion of hepatotoxins (mushrooms, carbon tetrachloride); or miscellaneous causes (Wilson's disease, idiopathic causes). Chronic liver failure can also result from several causes. Patients with disorders included in the following list have been shown to have excellent results following liver transplantation: chronic active hepatitis due to autoimmune hepatitis or chronic hepatitis C virus infection; alcoholic liver disease; metabolic diseases (α 1 -antitrypsin deficiency, hemochromatosis, Wilson's disease); cholestatic liver disorders (primary biliary cirrhosis, primary sclerosing cholangitis, biliary atresia); miscellaneous disorders (Budd-Chiari syndrome, polycystic liver disease, liver disease secondary to jejunoileal bypass); or cryptogenic cirrhosis. Liver transplantation is the most effective treatment for patients with fulminant hepatitis who have evidence of profound synthetic failure and hepatic encephalopathy. Patients with hepatocellular carcinoma and cholangiocarcinoma are also potential candidates for liver transplantation. These patients must have disease confined to their liver and be able to undergo adjunctive therapy postoperatively. Absolute contraindications for liver transplantation include AIDS, extrahepatic malignant tumors, and active intravenous drug use or alcohol abuse.
Databáze: OpenAIRE