Anterior quadratus lumborum block for ambulatory laparoscopic cholecystectomy: a randomized controlled trial
| Autor: | Marie Sørenstua, Jan Sverre Vamnes, Birgitte Sterud, Ann-Chatrin Leonardsen, Knut Inge Solbakk |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pain
Postoperative Nausea Opioid consumption business.industry Nerve Block General Medicine law.invention Randomized controlled trial Cholecystectomy Laparoscopic law Block (telecommunications) Anesthesia Ambulatory medicine Vomiting Humans medicine.symptom Analgesia Anesthetics Local business Laparoscopic cholecystectomy Research Article |
| Zdroj: | Croatian Medical Journal Volume 62 Issue 2 |
| ISSN: | 1332-8166 0353-9504 |
| Popis: | Aim To explore the effects of an anterior quadratus lumborum block (QLB) on opioid consumption, pain, nausea, and vomiting (PONV) after ambulatory laparoscopic cholecystectomy. Methods This randomized controlled study recruited 70 patients scheduled for ambulatory laparoscopic cholecystectomy from January 2018 to March 2019. The participants were randomly allocated to one of the following groups: 1) anterior QLB (n = 25) with preoperative ropivacaine 3.75 mg/mL, 20 mL bilaterally; 2) placebo QLB (n = 22) with preoperative isotonic saline, 20 mL bilaterally; and 3) controls (n = 23) given only standard intravenous and oral analgesia. The primary endpoint was opioid analgesic consumption. The secondary endpoints were pain (numeric rating scale 0-10) and PONV (scale 0-3, where 0 = no PONV and 3 = severe PONV). Assessments were made up to 48 hours postoperatively. Results The groups did not significantly differ in opioids consumption and reported pain at 1, 2, 24, and 48 hours postoperatively. PONV in the QLB group was lower than in the placebo and control groups. Conclusion Preoperative anterior QLB for laparoscopic cholecystectomy did not affect postoperative opioid requirements and pain. However, anterior QLB may decrease PONV. Clinical Trial number NCT03437187; January 22, 2018. |
| Databáze: | OpenAIRE |
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