Autonomic nervous tone in vitiligo patients--a case-control study
| Autor: | Peter Michael Rohrer, Michael Dennis Linder, J Baulmann, Angelika Hofer, Peter Wolf, Michael Trapp, Josef W. Egger, Hans Peter Kapfhammer, Francesca Sampogna, Erika Richtig, Eva Maria Trapp |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Vitiligo Dermatology Autonomic Nervous System Arousal Electrocardiography Heart Rate Internal medicine Heart rate medicine D2 Test of Attention Heart rate variability Humans Attention Exercise Balance (ability) medicine.diagnostic_test business.industry Case-control study General Medicine medicine.disease Bicycling Endocrinology Cross-Sectional Studies Case-Control Studies Cardiology Exercise Test Female business Stress Psychological |
| Zdroj: | Acta dermato-venereologica. 95(2) |
| ISSN: | 1651-2057 |
| Popis: | In this cross-sectional, exploratory case-control study the vegetative arousal in vitiligo patients compared to an age and gender matched healthy control group was assessed. Forty-eight participants (24 outpatients with generalised vitiligo and 24 healthy controls) completed a test procedure consisting of an initial period of rest (R1), a defined mental stress task (the d2 test of attention), a second period of rest (R2) followed by an individually, age adapted physical stress task (bicycle ergometry) and a final period of rest (R3). Based on a continuously recorded electrocardiogram, heart rate variability, in particular high frequency (HF) and low frequency (LF) components were determined. Within the 3 periods of rest, vitiligo patients showed a higher vegetative arousal than controls, represented by the ratio of LF/HF which mirrors the sympatho-vagal balance (R1: p = 0.027; R2: p = 0.003; R3: p = 0.029). No differences between the 2 groups were found during the mental (p = 0.187) and the physical stress task (p = 0.773). The results suggest a higher vegetative arousal in vitiligo patients. |
| Databáze: | OpenAIRE |
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