Chronic Thromboembolic Pulmonary Hypertension and Antiphospholipid Syndrome with Immune Thrombocytopenia: A Case Report
| Autor: | Matiss Sablinskis, Irene M Lang, Andris Skride, Walter Klepetko, Kristaps Sablinskis, Sandra Lejniece, Aivars Lejnieks |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Hypertension Pulmonary 030204 cardiovascular system & hematology 03 medical and health sciences Young Adult 0302 clinical medicine Immune system Antiphospholipid syndrome Internal medicine medicine Humans Platelet Young adult Purpura Thrombocytopenic Idiopathic biology business.industry General Medicine Articles medicine.disease Antiphospholipid Syndrome Immune thrombocytopenia Purpura 030228 respiratory system biology.protein Cardiology Chronic thromboembolic pulmonary hypertension Antibody medicine.symptom business Pulmonary Embolism |
| Zdroj: | The American Journal of Case Reports |
| ISSN: | 1941-5923 |
| Popis: | Patient: Male, 23 Final Diagnosis: Antiphospholipid syndrome Symptoms: Dyspnea Medication: — Clinical Procedure: Right heart catheterization Specialty: General and Internal Medicine Objective: Rare disease Background: Antiphospholipid syndrome is an autoimmune disorder characterized by a hypercoagulable state associated with circulating antiphospholipid antibodies. The presence of antiphospholipid antibodies can result in a variety of clinical symptoms, such as thrombocytopenia, stillbirth, endocardial pathologies, and recurrent pulmonary embolism. Case Report: We present the case of a 23-year-old man with antiphospholipid syndrome and chronic thromboembolic pulmonary hypertension who developed severe thrombocytopenia. The patient died from right heart failure before the thrombocytopenia could be managed, preventing performance of a pulmonary endarterectomy procedure. Conclusions: Managing platelet counts in patients with antiphospholipid syndrome prior to major surgery is very problematic, and requires similar treatment strategy as in patients with immune thrombocytic thrombocytopenia. Platelet transfusions may further decrease platelet count, as it can trigger formation of new antibodies. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|