Carry-over and contamination of veterinary drugs in feed production lines for poultry and pigs
| Autor: | Heitor Daguer, Ivan Bianchi, Luciano Molognoni, Maila Palmeira, Marcos Back, Vanessa Peripolli, André Barbosa da Silva, Leandro Antunes de Sá Ploêncio |
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| Rok vydání: | 2019 |
| Předmět: |
Active ingredient
0303 health sciences Veterinary Drugs 030306 microbiology Swine Health Toxicology and Mutagenesis Nutritional composition Public Health Environmental and Occupational Health Food Contamination General Chemistry General Medicine Contamination Biology Toxicology Poultry 03 medical and health sciences Production model Disease risk Animals Poultry Products 030304 developmental biology Food Science |
| Zdroj: | Food additivescontaminants. Part A, Chemistry, analysis, control, exposurerisk assessment. 36(5) |
| ISSN: | 1944-0057 |
| Popis: | The current model of pigs and poultry production has increased stocking density and reduced downtime between lots. This scenario may favour a rise of infection and disease risk in animals. To avoid this problem, routine use of drugs has been made, intensifying the possibility of residues in animal products and antimicrobial resistance. The aim of this study was to measure carry-over and contaminants of veterinary drugs included in the feed production lines for poultry and pigs. Samples were taken from 25 production lines. LC-MS/MS was used for simultaneous analysis of 62 active ingredients. In the medicated feed, 80.4% of the samples had a concentration of active ingredients different from the stated doses. In 70% of the feed samples, there was heterogeneity in the mixture of active ingredients. In subsequent feeds, carry-over was greater than 1% of the stated dose in 63% of cases. Of the 25 analysed lines, only one showed no contamination with other active ingredients. No correlations were found between the nutritional composition of the feed and carry-over. The present study demonstrated that the current production model allows the occurrence of unwanted drugs in feed-in doses that can contaminate animal products and can select antimicrobial-resistant bacteria. |
| Databáze: | OpenAIRE |
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