Vitamin D and Cardiovascular Risk: Which Implications in Children?
| Autor: | Gianni Bona, Francesco Tagliaferri, Silvia Savastio, Ivana Rabbone, Roberta Degrandi, Erica Pozzi, Roberta Cinquatti |
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| Rok vydání: | 2020 |
| Předmět: |
cardiovascular risk
extra-skeletal effects Physiology vitamin D 030209 endocrinology & metabolism Inflammation Review Disease 030204 cardiovascular system & hematology Models Biological Catalysis vitamin D deficiency law.invention lcsh:Chemistry Inorganic Chemistry 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Risk Factors law Vitamin D and neurology Humans Medicine Physical and Theoretical Chemistry Child lcsh:QH301-705.5 Molecular Biology Spectroscopy childhood Vitamin d supplementation business.industry Organic Chemistry General Medicine Vitamin D Deficiency medicine.disease Computer Science Applications Blood pressure lcsh:Biology (General) lcsh:QD1-999 Cardiovascular Diseases Dietary Supplements Arterial stiffness medicine.symptom business |
| Zdroj: | International Journal of Molecular Sciences, Vol 21, Iss 3536, p 3536 (2020) International Journal of Molecular Sciences |
| ISSN: | 1422-0067 |
| DOI: | 10.3390/ijms21103536 |
| Popis: | Vitamin D (25OHD) pleiotropic effects are widely recognized and studied. Recently, vitamin D cardiovascular effects are gaining interest, especially in children, although the studies present conflicting data. Some randomized controlled trials (RCTs) have demonstrated that cardiovascular risk markers, such as lipid parameters, inflammation markers, blood pressure, and arterial stiffness, are unaffected by vitamin D supplementation. By contrast, other studies show that low vitamin D levels are associated with higher risk of cardiovascular disease (CVD) and mortality, and support that increased risk of these diseases occurs primarily in people with vitamin D deficiency. An update on these points in pediatric patients is certainly of interest to focus on possible benefits of its supplementation. |
| Databáze: | OpenAIRE |
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