Effects of Sustained Lung Inflation, a lung recruitment maneuver in primary acute respiratory distress syndrome, in respiratory and cerebral outcomes in preterm infants
| Autor: | P Betta, Valentina Giacchi, Sciacca P, Grazia Maria Palano, Carmine Mattia, Chiara Grasso, Caterina Carpinato |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Child Development Fraction of inspired oxygen Intubation Intratracheal medicine Humans Neonatology Cerebral Hemorrhage Respiratory Distress Syndrome Newborn Periventricular leukomalacia business.industry Infant Newborn Obstetrics and Gynecology medicine.disease Respiration Artificial Intraventricular hemorrhage Bronchopulmonary dysplasia Pneumothorax Case-Control Studies Anesthesia Pediatrics Perinatology and Child Health Necrotizing enterocolitis Female business Infant Premature Neonatal resuscitation |
| Zdroj: | Early Human Development. 91:71-75 |
| ISSN: | 0378-3782 |
| DOI: | 10.1016/j.earlhumdev.2014.12.002 |
| Popis: | Sustained Lung Inflation (SLI) is a maneuver of lung recruitment in preterm newborns at birth that can facilitate the achieving of larger inflation volumes, leading to the clearance of lung fluid and formation of functional residual capacity (FRC).To investigate if Sustained Lung Inflation (SLI) reduces the need of invasive procedures and iatrogenic risks.78 newborns (gestational age≤34 weeks, weighing≤2000 g) who didn't breathe adequately at birth and needed to receive SLI in addition to other resuscitation maneuvers (2010 guidelines).78 preterm infants born one after the other in our department of Neonatology of Catania University from 2010 to 2012.The need of intubation and surfactant, the ventilation required, radiological signs, the incidence of intraventricular hemorrhage (IVH), periventricular leukomalacia, retinopathy in prematurity from III to IV plus grades, bronchopulmonary dysplasia, patent ductus arteriosus, pneumothorax and necrotizing enterocolitis.In the SLI group infants needed less intubation in the delivery room (6% vs 21%; p0.01), less invasive mechanical ventilation (14% vs 55%; p≤0.001) and shorter duration of ventilation (9.1 days vs 13.8 days; p≤0.001). There wasn't any difference for nasal continuous positive airway pressure (82% vs 77%; p=0.43); but there was less surfactant administration (54% vs 85%; p≤0.001) and more infants received INSURE (40% vs 29%; p=0.17). We didn't found any differences in the outcomes, except for more mild intraventricular hemorrhage in the SLI group (23% vs 14%; p=0.15; OR=1.83).SLI is easier to perform even with a single operator, it reduces the necessity of more complicated maneuvers and surfactant without statistically evident adverse effects. |
| Databáze: | OpenAIRE |
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