Surgical resection of oral cancer: en-bloc versus discontinuous approach
| Autor: | Alice Piccinato, Giancarlo Tirelli, Alberto Vito Marcuzzo, Margherita Tofanelli, Annalisa Gatto, Paolo Antonucci |
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| Přispěvatelé: | Tirelli, G., Piccinato, A., Antonucci, P., Gatto, A., Marcuzzo, A. V., Tofanelli, M. |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Compartmental surgery Neck dissection Oral cancer Transoral surgery T–N tract Quality of life Tongue medicine Humans Minimally Invasive Surgical Procedures Survival analysis business.industry Cancer General Medicine medicine.disease Surgery medicine.anatomical_structure Treatment Outcome Otorhinolaryngology Quality of Life Anxiety Mouth Neoplasms Neurosurgery medicine.symptom Neoplasm Recurrence Local business |
| Popis: | Objectives: In the past literature agreed on treating oral carcinomas, using an “en-bloc” resection (EBR) but recently minimally invasive transoral surgery has spread as the preferable treatment for selected cases. This latter technique, which is performed with a discontinuous resection (DR), allows for a satisfactory postoperative quality of life (QoL) maintaining good survival rates. Materials and methods: In this study, we analyzed data about 147 surgically treated patients with oral cancer involving tongue and floor of the mouth. The sample was divided according to the surgical approach: EBR and DR group which were compared in terms of recurrence, overall survival, disease-free survival, and QoL. Results: In the DR group, survival analysis showed better results in term of survival, locoregional control, and postoperative anxiety, while the other QoL scores were similar in the two groups. Conclusion: The more invasive approach does not correlate to a better outcome. In selected cases, DR is an oncologically safe technique; EBR is still a valid option to treat advanced oral cancers. |
| Databáze: | OpenAIRE |
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