Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men

Autor: Mirela Casonato Roveratti, Walquíria Batista de Andrade, Andreo Fernando Aguiar, Douglas Kratki da Silva, José Maria Estoche, Mario Carlos Welin Balvedi, Rubens Alexandre da Silva, Douglas Bendito Oliveira, Jeferson Lucas Jacinto
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Male
Time Factors
Hydrocortisone
Malates
chemistry.chemical_compound
0302 clinical medicine
Citrulline
Testosterone
Creatine Kinase
Nutrition and Dietetics
Cross-Over Studies
biology
exercise
weight training
medicine.anatomical_structure
Treatment Outcome
Muscle Fatigue
medicine.symptom
lcsh:Nutrition. Foods and food supply
Muscle contraction
Muscle Contraction
Adult
medicine.medical_specialty
Strength training
lcsh:TX341-641
Placebo
Article
03 medical and health sciences
Young Adult
supplementation
skeletal muscle
amino acids
protein
Double-Blind Method
Internal medicine
medicine
Humans
Lactic Acid
Muscle
Skeletal

Muscle fatigue
business.industry
Skeletal muscle
Resistance Training
030229 sport sciences
Recovery of Function
Crossover study
Endocrinology
chemistry
Dietary Supplements
biology.protein
Creatine kinase
business
030217 neurology & neurosurgery
Biomarkers
Food Science
Zdroj: Nutrients
Nutrients; Volume 9; Issue 10; Pages: 1132
Nutrients, Vol 9, Iss 10, p 1132 (2017)
ISSN: 2072-6643
Popis: The effects of citrulline malate (CM) on muscle recovery from resistance exercise remains unknown. We aimed to determine if citrulline malate supplementation improves muscle recovery after a single session of high-intensity resistance exercise (RE) in untrained young adult men. Nine young adult men (24.0 ± 3.3 years) participated in a double-blind crossover study in which they received 6 g of CM and placebo (PL) on two occasions, separated by a seven-day washout period. Each occasion consisted of a single session of high-intensity RE (0 h) and three subsequent fatigue tests sessions (at 24, 48, and 72 h) to assess the time course of muscle recovery. During the tests sessions, we assessed the following variables: number of maximum repetitions, electromyographic signal (i.e., root mean square (RMS) and median frequency (MF)), muscle soreness and perceived exertion, as well as blood levels of creatine kinase (CK), lactate, insulin, and testosterone:cortisol ratio. CK levels increased at 24 h post-exercise and remained elevate at 48 and 72 h, with no difference between CM and PL conditions. Muscle soreness increased at 24 h post-exercise, which progressively returned to baseline at 72 h in both conditions. Lactate levels increased immediately post-exercise and remained elevated at 24, 48, and 72 h in both conditions. No significant treatment × time interaction was found for all dependents variables (maximum repetitions, perceived exertion, CK, lactate, RMS, MF, and testosterone:cortisol ratio) during the recovery period. In conclusion, our data indicate that CM supplementation (single 6 g dose pre-workout) does not improve the muscle recovery process following a high-intensity RE session in untrained young adult men.
Databáze: OpenAIRE