On the antigenic diversity threshold model for aids
| Autor: | Nikolaos I. Stilianakis, Dieter Schenzle, Klaus Dietz |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Statistics and Probability
Time Factors Stochastic modelling Human immunodeficiency virus (HIV) medicine.disease_cause Models Biological General Biochemistry Genetics and Molecular Biology Model dynamics Antigenic Diversity Econometrics Humans Medicine Acquired Immunodeficiency Syndrome Stochastic Processes General Immunology and Microbiology business.industry Applied Mathematics HIV General Medicine Antigenic Variation Modeling and Simulation Immunology Threshold model General Agricultural and Biological Sciences business Mathematics |
| Zdroj: | Mathematical Biosciences. 121:235-247 |
| ISSN: | 0025-5564 |
| Popis: | In this paper stochastic simulations of a model for AIDS pathogenesis developed by Nowak and coworkers are presented. The results reveal a strong dependency on initial conditions, and the model predicts a nonmonotonic hazard rate for the transition to AIDS. Doubts are raised concerning the significance of the “antigenic diversity threshold,” since it only partially characterizes the model dynamics. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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