Consecutive evaluation of immunoglobulin M and G antibodies against hepatitis E virus
| Autor: | Jian-Guo Li, Hak Hotta, Wel-Min Ke, Yoshitake Shinji, De Tan, Ji-Lu Yao, Satoru Izumi |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty viruses Enzyme-Linked Immunosorbent Assay medicine.disease_cause Hepatitis E virus Recurrence Risk Factors Internal medicine medicine Humans In patient Hepatitis Antibodies Retrospective Studies biology business.industry Acute hepatitis E Gastroenterology virus diseases Hepatology digestive system diseases Hepatitis E Immunoglobulin M Southern china Immunoglobulin G Acute Disease Immunology biology.protein Female Antibody business Biomarkers Acute hepatitis |
| Zdroj: | Journal of Gastroenterology. 31:818-822 |
| ISSN: | 1435-5922 0944-1174 |
| DOI: | 10.1007/bf02358608 |
| Popis: | Hepatitis E virus (HEV) infection is sporadic in the Guangzhou city southern China. However, the evaluation of antibodies to HEV during consecutive time periods after infection has not been reported. We utilized enzyme immunosorbent assay (ELISA) to detect IgM and IgG anti-HEV in consecutive serum specimens from patients with acute hepatitis E and compared that data with detection rates of IgM and IgG anti-HAV in patients with acute hepatitis A. IgM anti-HEV can be detected as early as 4 days after onset of disease symptoms in some patients. The detection rate of IgM anti-HEV is significantly higher in specimens collected within 4 weeks (95%) of onset than in those specimens collected 4 to 18 weeks after onset (67.6%) (P |
| Databáze: | OpenAIRE |
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