Prognostic Value of High-Sensitivity C-Reactive Protein, Procalcitonin and Pancreatic Stone Protein in Pediatric Sepsis
| Autor: | Qiong Wu, Feng-yi Chen, Fu-xia Wu, Jun Nie, Xiu-lan Zou |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Calcitonin
Male medicine.medical_specialty Multivariate analysis Logistic regression Gastroenterology Procalcitonin Sepsis 03 medical and health sciences 0302 clinical medicine Pediatric sepsis Risk Factors Clinical Research Internal medicine parasitic diseases Lithostathine medicine Humans 030212 general & internal medicine Child biology business.industry C-reactive protein Infant 030208 emergency & critical care medicine General Medicine medicine.disease Prognosis eye diseases Surgery C-Reactive Protein Logistic Models ROC Curve Child Preschool Multivariate Analysis Pancreatin biology.protein Biomarker (medicine) Pancreatic stone protein Female business hormones hormone substitutes and hormone antagonists |
| Zdroj: | Medical Science Monitor : International Medical Journal of Experimental and Clinical Research |
| ISSN: | 1643-3750 |
| Popis: | BACKGROUND To investigate the prognostic value of procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP), and pancreatic stone protein (PSP) in children with sepsis. MATERIAL AND METHODS A total of 214 patients with sepsis during hospitalization were enrolled. Serum levels of PCT, hs-CRP, and PSP were measured on day 1 of hospitalization and the survival rates of children were recorded after a follow-up of 28 days. Pearson's correlation analysis was conducted to test the association of PCT, hs-CRP, and PSP with pediatric critical illness score (PCIS). Logistic regression models were used to analyze the risk factors contributing to patients' death. The AUC was used to determine the value of PCT, hs-CRP, and PSP in the prognosis of patients with sepsis. RESULTS The expression of PCT, hs-CRP, and PSP in the dying patients was higher than in the surviving patients (p |
| Databáze: | OpenAIRE |
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