Management of Wet Age-Related Macular Degeneration in Spain: Challenges for Treat and Extend Implementation in Routine Clinical Practice

Autor: A. García-Layana, J. García-Arumí, M. S. Figueroa, L. Arias Barquet, J. M. Ruíz-Moreno, L. Monclús-Arbona, null The Spanish AMD Multicenter Group
Přispěvatelé: [García-Layana A] Clínica Universidad de Navarra, Pamplona, Spain. [García-Arumí J] Servei d’ Oftalmologia, Vall d'Hebron Hospital Universitari, Barcelona, Spain. [Figueroa MS] Vissum Madrid, Madrid, Spain. [Arias Barquet L] Hospital de Bellvitge, L'Hospitalet de Llobregat, Spain. [Ruíz-Moreno JM] Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain. [Monclús-Arbona L] Bayer Hispania, S.L., Sant Joan Despí, Spain, Vall d'Hebron Barcelona Hospital Campus, UAM. Departamento de Cirugía
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Delphi method
Two-round study questionnaire
Therapeutics::Clinical Protocols [ANALYTICAL
DIAGNOSTIC AND THERAPEUTIC TECHNIQUES
AND EQUIPMENT]
0302 clinical medicine
Retina specialists experienced
lcsh:Ophthalmology
Health care
Equips d'especialistes - Espanya
Duration (project management)
Degeneració (Patologia)
Aflibercept
Proactive treatment patterns
Standard treatment
Degeneration (Pathology)
Retinal diseases
Geographic Locations::Europe::Spain [GEOGRAPHICALS]
Malalties de la retina
Ciencias de la información::análisis de sistemas::técnica Delfos [CIENCIA DE LA INFORMACIÓN]
Information Science::Systems Analysis::Delphi Technique [INFORMATION SCIENCE]
Ubicaciones Geográficas::Europa (Continente)::España [DENOMINACIONES GEOGRÁFICAS]
Medical emergency
Protocols clínics
medicine.drug
Research Article
Article Subject
Medicina
wAMD)
MEDLINE
Retina specialists
terapéutica::protocolos clínicos [TÉCNICAS Y EQUIPOS ANALÍTICOS
DIAGNÓSTICOS Y TERAPÉUTICOS]
03 medical and health sciences
oftalmopatías::enfermedades de la retina::degeneración retiniana::degeneración macular::degeneración macular exudativa [ENFERMEDADES]
Eye Diseases::Retinal Diseases::Retinal Degeneration::Macular Degeneration::Wet Macular Degeneration [DISEASES]
Ranibizumab
medicine
Dosing
Espanya
business.industry
Macular degeneration
medicine.disease
Ophthalmology
Spain
lcsh:RE1-994
030221 ophthalmology & optometry
Anti-VEGF administration
business
030217 neurology & neurosurgery
Degeneració macular
Zdroj: Scientia
Journal of Ophthalmology, Vol 2019 (2019)
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Journal of Ophthalmology
Biblos-e Archivo. Repositorio Institucional de la UAM
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
ISSN: 2090-004X
DOI: 10.1155/2019/9821509
Popis: Purpose. To ascertain wet AMD (wAMD) management patterns in Spain. Methods. A two-round Delphi study conducted through a questionnaire-based survey designed from literature review and validated by an independent Steering Committee. Results. Forty-nine retina specialists experienced in wAMD participated by answering the two-round study questionnaire. Retina specialists are the main responsible for wAMD diagnosis and monitoring, including visits and associated procedures, with a median time per visit of 15 minutes. Standard treatment strategies are based on anti-VEGF administration, including standard loading dose administration followed by maintenance with aflibercept or ranibizumab (81% of patients). Although treat and extend (T&E) dosing strategy is considered as optimal for wAMD management (78% of the panelists), the main routine healthcare limitations (i.e., visits overload, reduced staff, short visit time, coordination issues, lack of facilities) conduct to self-defined “flexible” strategies, based on T&E and pro-re-nata (PRN) protocols. Conclusion. Proactive treatment patterns (T&E) are the preferred ones by the retina specialists in Spain. However, their proper implementation is difficult due to healthcare resource limitations, as well as organisation and logistic issues. .e use of anti-VEGF agents with longer duration of action could facilitate the use of strict T&E approaches according to routine clinical practices
The study has been sponsored by Bayer Hispania S.L. Logistics
Databáze: OpenAIRE
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