| Autor: |
T. Bence Viola, Cesare de Filippo, Svante Pääbo, Janet Kelso, Kay Prüfer, Pavel A. Kosintsev, Jean-Jacques Hublin, Qiaomei Fu, Ayinuer Aximu-Petri, Montgomery Slatkin, Yaroslav V. Kuzmin, Nicolas Zwyns, Susan G. Keates, Nikolai V. Peristov, Priya Moorjani, Philip L. F. Johnson, Aleksei A. Bondarev, Michael P. Richards, Heng Li, Matthias Meyer, Domingo C. Salazar-García, Katerina Douka, Michael Lachmann, David Reich, Dmitry Razhev, Flora Jay, Sergey Mikhailovich Slepchenko, Thomas Higham |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Nature
Nature, vol 514, iss 7523 |
| ISSN: |
0028-0836 |
| DOI: |
10.1038/nature13810 |
| Popis: |
We present the high-quality genome sequence of a ∼45,000-year-old modern human male from Siberia. This individual derives from a population that lived before-or simultaneously with-the separation of the populations in western and eastern Eurasia and carries a similar amount of Neanderthal ancestry as present-day Eurasians. However, the genomic segments of Neanderthal ancestry are substantially longer than those observed in present-day individuals, indicating that Neanderthal gene flow into the ancestors of this individual occurred 7,000-13,000 years before he lived. We estimate an autosomal mutation rate of 0.4×10(-9) to 0.6×10(-9) per site per year, a Y chromosomal mutation rate of 0.7×10(-9) to 0.9×10(-9) per site per year based on the additional substitutions that have occurred in present-day non-Africans compared to this genome, and a mitochondrial mutation rate of 1.8×10(-8) to 3.2×10(-8) per site per year based on the age of the bone. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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