General anesthesia with remimazolam in a patient with mitochondrial encephalomyopathy: a case report
| Autor: | Yoshiki Nakajima, Matsuyuki Doi, Yuji Suzuki |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Mitochondrial encephalomyopathy
Flumazenil medicine.medical_specialty Sedation Remifentanil Case Report 03 medical and health sciences 0302 clinical medicine 030202 anesthesiology Anesthesiology medicine RD78.3-87.3 Mitochondrial myopathy Remimazolam business.industry RC86-88.9 Medical emergencies. Critical care. Intensive care. First aid Perioperative medicine.disease Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes Anesthesiology and Pain Medicine Muscle relaxation Anesthesia Lactic acidosis medicine.symptom business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | JA Clinical Reports JA Clinical Reports, Vol 7, Iss 1, Pp 1-3 (2021) |
| ISSN: | 2363-9024 |
| Popis: | Background Systemic anesthetic management of patients with mitochondrial disease requires careful preoperative preparation to administer adequate anesthesia and address potential disease-related complications. The appropriate general anesthetic agents to use in these patients remain controversial. Case presentation A 54-year-old woman (height, 145 cm; weight, 43 kg) diagnosed with mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes underwent elective cochlear implantation. Infusions of intravenous remimazolam and remifentanil guided by patient state index monitoring were used for anesthesia induction and maintenance. Neither lactic acidosis nor prolonged muscle relaxation occurred in the perioperative period. At the end of surgery, flumazenil was administered to antagonize sedation, which rapidly resulted in consciousness. Conclusions Remimazolam administration and reversal with flumazenil were successfully used for general anesthesia in a patient with mitochondrial disease. |
| Databáze: | OpenAIRE |
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