Evolution of the SYNERGY bioresorbable polymer metallic coronary stent
| Autor: | Satya Shreenivas, Dean J. Kereiakes |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Polymers
Polyesters medicine.medical_treatment Bioresorbable polymers Coronary Artery Disease 030204 cardiovascular system & hematology Prosthesis Design 03 medical and health sciences 0302 clinical medicine Coated Materials Biocompatible Absorbable Implants Coronary stent Humans Medicine cardiovascular diseases 030212 general & internal medicine Platinum Everolimus Metal alloy business.industry Stent Drug-Eluting Stents equipment and supplies Clinical Practice surgical procedures operative Drug-eluting stent Molecular Medicine Chromium Alloys Cardiology and Cardiovascular Medicine business medicine.drug Biomedical engineering |
| Zdroj: | Future Cardiology. 14:307-317 |
| ISSN: | 1744-8298 1479-6678 |
| Popis: | The SYNERGY stent is composed of thin, platinum-chromium metal alloy struts and an ultrathin, bioabsorbable poly-DL-lactide-co-glycolide polymer limited to the abluminal strut surface which elutes everolimus prior to complete resorption within 3–4 months. SYNERGY was designed to reduce inflammation and facilitate stent healing compared with permanent polymer drug eluting stents. This review summarizes the preclinical and clinical development of SYNERGY, its integration into clinical practice and future directions. |
| Databáze: | OpenAIRE |
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