Medication Adherence Aligns with Age and a Behavioral Checklist but Not Symptoms or Quality of Life for Patients with Eosinophilic Esophagitis

Autor: Calies Menard-Katcher, Pooja Mehta, Zhaoxing Pan, Bethany M. Kwan, Stephanie Skirka
Rok vydání: 2021
Předmět:
Zdroj: J Pediatr
ISSN: 0022-3476
Popis: OBJECTIVE: To measure adherence rates to swallowed topical steroids in children with eosinophilic esophagitis (EoE), describe factors related to adherence, and determine the association between adherence, symptoms, perceived disease severity, and quality of life in children with EoE. STUDY DESIGN: Subjects in this cross-sectional study of 117 children between 5–18 years old with EoE completed the Pediatric Eosinophilic Esophagitis Symptoms Score V2.0 (PEESS), Pediatric Quality of Life Inventory Eosinophilic Esophagitis Module (PedsQL EoE), a Medication-Taking Checklist (MTC), and a demographics questionnaire. Adherence rate was calculated based on reported number of missed doses/prescribed doses in the last week. Parent-reported measures were used for children aged 5–12 years and self-report was used for children aged 13–18 years. RESULTS: Adolescents had lower adherence rates than younger children (76.2 ± 24.5% versus 88.6 ± 16.7%, P =.002). Adherence rates were not associated with disease history, PEESS or PedsQL™ EoE scores, but instead correlated with MTC scores (Pearson r o f0.65, P
Databáze: OpenAIRE