New modified version of the Risk Adjustment for Congenital Heart Surgery category and mortality in premature infants with critical congenital heart disease
| Autor: | Ee Kyung Kim, Seong Phil Bae, Jae Gun Kwak, Seung Han Shin, Mi Kyoung Song, Young Mi Yoon, Han Suk Kim, Woong Han Kim, Yoon Joo Kim |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Neonatal intensive care unit Late preterm infant business.industry Birth weight lcsh:RJ1-570 Gestational age lcsh:Pediatrics Neonatology (Perinatology) medicine.disease Pediatrics Surgery Low birth weight Bronchopulmonary dysplasia Intensive care Pediatrics Perinatology and Child Health Medicine Original Article Mortality medicine.symptom Critical congenital heart disease business Premature Congenital heart disease Outcome |
| Zdroj: | Clinical and Experimental Pediatrics Clinical and Experimental Pediatrics, Vol 63, Iss 10, Pp 395-401 (2020) |
| ISSN: | 2713-4148 |
| DOI: | 10.3345/cep.2019.01522 |
| Popis: | Background: Despite advances in neonatal intensive care and surgical procedures, perinatal mortality rates for premature infants with congenital heart disease (CHD) remain relatively high.Purpose: We aimed to describe the outcomes of premature infants with critical CHD and identify the risk factors including the new modified version of the Risk Adjustment for Congenital Heart Surgery (M-RACHS) category associated with in-hospital mortality in a Korean tertiary center.Methods: This was a retrospective cohort study of premature infants with critical CHD admitted to the neonatal intensive care unit from January 2005 to December 2016.Results: A total of 78 premature infants were enrolled. The median gestational age (GA) at birth was 34.9 weeks (range, 26.7–36.9 weeks), and the median birth weight was 1.91 kg (range, 0.53–4.38 kg). Surgical or percutaneous intervention was performed in 68 patients with a median GA at birth of 34.7 weeks (range, 26.7–36.8 weeks) and a median birth weight of 1.92 kg (range, 0.53–4.38 kg). The in-hospital survival rate was 76.9% among all enrolled preterm infants and 86.8% among patients who received an intervention. Very low birth weight (VLBW), persistent pulmonary hypertension of the newborn (PPHN), bronchopulmonary dysplasia (BPD), and M-RACHS category 5 or higher (more complex CHD) were independently associated with in-hospital mortality. For the 68 premature infants undergoing cardiac interventions, independent risk factors for mortality were VLBW, BPD, and CHD complexity. Late preterm infant and age at intervention were not associated with patient survival.Conclusion: For premature infants with critical CHD, VLBW, PPHN, BPD, and M-RACHS category ≥5 were risk factors for mortality. A careful approach to surgical intervention and prenatal care should be taken according to CHD type and neonatal condition. |
| Databáze: | OpenAIRE |
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