Regional variations of ultrasonic integrated backscatter in normal and myopathicleft ventricles. A new multi-view approach
| Autor: | K P Bouki, Aleksandra Lange, William McDicken, L N Fenn, Carmel M. Moran, Robert A. Wright, Keith A.A. Fox, G. R. Sutherland, Przemysław Palka |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Cardiomyopathy Dilated Male medicine.medical_specialty Cardiomyopathy Internal medicine Idiopathic dilated cardiomyopathy medicine Humans Prospective Studies Aged Geographic difference Observer Variation Ejection fraction business.industry Myocardium Middle Aged medicine.disease Myocardial Contraction Echocardiography Doppler medicine.anatomical_structure Echocardiography Ventricle Parasternal line Circulatory system Cardiology Female Cardiology and Cardiovascular Medicine business Apical four chamber view |
| Zdroj: | European Heart Journal. 17:1747-1755 |
| ISSN: | 1522-9645 0195-668X |
| Popis: | The purpose of the present study was to determine whether the cyclic variation of integrated backscatter is measurable and quantifiable in all left ventricular walls and whether the information obtained using both parasternal and apical transducer positions can be used to identify changes in myocardial structure and contractility. The cyclic variation of integrated backscatter was measured from the parasternal long-axis, apical four-chamber and two-chamber views in 26 patients with idiopathic dilated cardiomyopathy (mean age 58 +/- 9 years; ejection fraction 29 +/- 10%) and compared with information obtained from 30 aged-matched healthy volunteers. For each subject, the cyclic variation of integrated backscatter was calculated from 16 predetermined regions-of-interest located within the myocardium of the basal and mid-segments of the left ventricle imaged from the long-axis view and also the basal mid and apical left ventricular segments imaged from the two apical views. The cyclic variation of integrated backscatter was found to be present in 100% of the analysed regions-of-interest in healthy volunteers and in 87.5% of the analysed regions-of-interest in patients with idiopathic dilated cardiomyopathy. The mean value of cyclic variation of integrated backscatter, averaged from all regions-of-interest in the idiopathic dilated cardiomyopathy group, was significantly reduced compared to that in the healthy volunteers group (3.2 +/- 2.5 dB [mean +/- SD] vs 4.8 +/- 2.9 dB, P0.0001). Additionally, the healthy volunteers group demonstrated marked regional variability in the magnitude of cyclic variation of integrated backscatter which closely followed the regional changes in the contractile function of the normal heart. These regional differences in the magnitude of the cyclic variation of integrated backscatter were only partially retained in the idiopathic dilated cardiomyopathy group, and suggest that a multi-view approach of the recording of cyclic variation of integrated backscatter can be of value to differentiate normal from myopathic myocardium and to quantify regional differences in myocardial contractile performance throughout the left ventricular walls. |
| Databáze: | OpenAIRE |
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