The how’s and what’s of vaccine reactogenicity
Autor: | Fernanda Tavares Da Silva, Caroline Hervé, Arnaud Didierlaurent, Béatrice Laupèze, Giuseppe Del Giudice |
---|---|
Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
myalgia
lcsh:Immunologic diseases. Allergy medicine.medical_specialty Immunology Review Article lcsh:RC254-282 03 medical and health sciences 0302 clinical medicine Vaccine administration Reducing anxiety 030225 pediatrics Injection site medicine Pharmacology (medical) 030212 general & internal medicine Signs and symptoms Intensive care medicine Pharmacology Vaccines Reactogenicity Health professionals business.industry Public health lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Vaccination Infectious Diseases medicine.symptom business lcsh:RC581-607 |
Zdroj: | npj Vaccines, Vol 4, Iss 1, Pp 1-11 (2019) NPJ Vaccines |
ISSN: | 2059-0105 |
Popis: | Reactogenicity represents the physical manifestation of the inflammatory response to vaccination, and can include injection-site pain, redness, swelling or induration at the injection site, as well as systemic symptoms, such as fever, myalgia, or headache. The experience of symptoms following vaccination can lead to needle fear, long-term negative attitudes and non-compliant behaviours, which undermine the public health impact of vaccination. This review presents current knowledge on the potential causes of reactogenicity, and how host characteristics, vaccine administration and composition factors can influence the development and perception of reactogenicity. The intent is to provide an overview of reactogenicity after vaccination to help the vaccine community, including healthcare professionals, in maintaining confidence in vaccines by promoting vaccination, setting expectations for vaccinees about what might occur after vaccination and reducing anxiety by managing the vaccination setting. |
Databáze: | OpenAIRE |
Externí odkaz: |