A Modified Simple Scoring System Using the Red Blood Cell Distribution Width, Delta Neutrophil Index, and Mean Platelet Volume-to-Platelet Count to Predict 28-Day Mortality in Patients With Sepsis
| Autor: | Jin Young Ahn, Jun Hyoung Kim, Yu Jin Sohn, Su Jin Jeong, Jun Yong Choi, Joon Sup Yeom, Yun Suk Cho, Nam Su Ku, Jung Ho Kim, Woon Ji Lee, Jong Hoon Hyun, Hye Seong, Sang Min Ahn, Yongseop Lee, Young Goo Song |
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| Rok vydání: | 2020 |
| Předmět: |
Delta
medicine.medical_specialty Scoring system Erythrocytes Neutrophils 030204 cardiovascular system & hematology Critical Care and Intensive Care Medicine Sepsis 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Platelet In patient Mean platelet volume Retrospective Studies business.industry Septic shock Platelet Count 030208 emergency & critical care medicine Red blood cell distribution width medicine.disease ROC Curve Cardiology business Mean Platelet Volume |
| Zdroj: | Journal of intensive care medicine. 36(8) |
| ISSN: | 1525-1489 |
| Popis: | Background: Recently, a new scoring system was developed that uses the red blood cell distribution width (RDW), delta neutrophil index (DNI), and platelet count (PC) to predict mortality in patients with sepsis. We investigated whether a modified simple scoring system based on the RDW, DNI, and mean platelet volume-to-PC (MPV/PC) ratio could predict the mortality of patients with sepsis, and compared it to the previous scoring system. Methods: We conducted a retrospective cohort study of 264 adults who had been treated for sepsis in an emergency department between January 2016 and February 2019. Each patient was rated on a scale of 0 to 3 according to the modified scoring system. Point values were assigned based on RDW > 14.5%, DNI > 5.0%, and MPV/PC ratio >10.1. Results: The 28-day mortality rate was 14.4%. Those who died had higher scores than those who survived (mean: 1.55 ± 0.92 vs 0.93 ± 0.78, P < .001). The area under the curve for the new scoring system was higher than that of the previous scoring system (0.685 vs 0.645). Conclusion: The modified scoring system was a good predictor of the 28-day mortality and was more useful than the previous scoring system for predicting mortality in patients with sepsis. |
| Databáze: | OpenAIRE |
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