New Type III CRISPR variant and programmable RNA targeting tool: Oh, thank heaven for Cas7-11
| Autor: | Michael P. Terns, Ryan J. Catchpole |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Mol Cell |
| Popis: | Ozcan et al. (2021) and van Beljouw et al. (2021) characterize a novel Type III-E CRISPR-Cas subtype, composed of a single polypeptide with crRNA processing and sequence-specific RNA cleavage activities, that provides a new RNA knockdown tool for mammalian cells with fewer off-target effects than current technologies. |
| Databáze: | OpenAIRE |
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