Seasonal changes in in vivo cortisol response to acth and in plasma and pituitary concentrations of ACTH in a desert rodent, the sand rat (Psammomys obesus)
| Autor: | R Brudieux, Z Amirat |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Pituitary gland Hydrocortisone Rodent Drug Administration Schedule Adrenocorticotropic Hormone Pituitary Gland Anterior In vivo Internal medicine biology.animal Adrenal Glands medicine Animals Secretion Rats Wistar biology Adrenal cortex Organ Size General Medicine biology.organism_classification Rats medicine.anatomical_structure Endocrinology Pituitary Gland Seasons Psammomys Corticosterone Gerbillinae hormones hormone substitutes and hormone antagonists Glucocorticoid medicine.drug |
| Zdroj: | Comparative Biochemistry and Physiology Part A: Physiology. 104:29-34 |
| ISSN: | 0300-9629 |
| DOI: | 10.1016/0300-9629(93)90004-n |
| Popis: | 1. 1. During spring, decreased sensitivity of the adrenal cortex to adrenocorticotrophic hormone (ACTH) in the sand rat inhabiting the Beni-Abbes area (Algeria), results in a reduction in the production of cortisol. Thus the secretion of ACTH is enhanced, becoming maximal in June and presumably also during the following weeks. 2. 2. Increase in ACTH secretion, together with a slightly increased adrenal sensitivity, is likely to stimulate corticosteroidogenesis throughout the summer. 3. 3. In autumn, as levels of cortisol are high, the negative feedback increases leading to a reduction in ACTH production. 4. 4. An increase in the adrenocortical sensitivity to ACTH allows a high production of cortisol until February. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|