Clinicopathologic importance of atypical glandular cells in cervico-vaginal cytology
| Autor: | Husnu Celik, Filiz Bolat, Selçuk Yetkinel, Erhan Simsek, Seda Yuksel, Songül Alemdaroğlu |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
pap smear
medicine.medical_specialty cervical cancer neoplasms lcsh:Medicine Epithelial cell abnormality Malignancy Gastroenterology lcsh:Gynecology and obstetrics 03 medical and health sciences 0302 clinical medicine Internal medicine Cytology medicine 030212 general & internal medicine Vaginal cytology lcsh:RG1-991 Original Investigation business.industry Incidence (epidemiology) lcsh:R Obstetrics and Gynecology Cervicovaginal cytology Patient data medicine.disease stomatognathic diseases 030220 oncology & carcinogenesis Cohort business |
| Zdroj: | Journal of the Turkish-German Gynecological Association, Vol 21, Iss 2, Pp 102-106 (2020) Journal of the Turkish German Gynecological Association |
| ISSN: | 1309-0380 1309-0399 |
| Popis: | Objective To analyze the histopathologic outcomes of patients with atypical glandular cells (AGC) in cervicovaginal cytology examinations. Material and methods Patients with AGC in cervicovaginal cytology were included in this study between March 2011 and March 2018 and patient data were collected retrospectively among all cytology results. AGC classification of cervicovaginal cytology were based on the Bethesda 2001 classification system. Results The total prevalence of cervical epithelial cell abnormality and AGC were found as 4.2% and 0.2%, respectively, in the study cohort. AGC-favor neoplasia (AGC-FN) was the subgroup of AGC with the highest malignancy rate with 62.5% (p=0.06). The incidence of malignancy in the postmenopausal group (33.3%) was detected higher than in the premenopausal group (8.3%) (p=0.07). Conclusion The probability of malignancy in AGC-FN cytology is more commonly associated with malignancy in the postmenopausal group. Therefore, histopathologic examination is strongly recommended in these patients with AGC smears because of the high risk for malignancy in this group. |
| Databáze: | OpenAIRE |
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