Optic Disc Parameters of Myopic Children with Atropine Treatment

Autor:	Li-Wei Chan, Han-Chih Cheng, Wei-Cherng Hsu, Yi-Ting Hsieh, Elizabeth P Shen
Rok vydání:	2017
Předmět:	Atropine Male Retinal Ganglion Cells Mydriatics Intraocular pressure medicine.medical_specialty Visual acuity Adolescent genetic structures Optic Disk Visual Acuity Nerve fiber layer 03 medical and health sciences Cellular and Molecular Neuroscience chemistry.chemical_compound Nerve Fibers 0302 clinical medicine Ophthalmology Myopia medicine Humans Child Intraocular Pressure Dioptre business.industry Retinal eye diseases Sensory Systems medicine.anatomical_structure chemistry Child Preschool 030221 ophthalmology & optometry Optic nerve Female sense organs medicine.symptom business Tomography Optical Coherence 030217 neurology & neurosurgery Follow-Up Studies medicine.drug Optic disc
Zdroj:	Current Eye Research. 42:1614-1619
ISSN:	1460-2202 0271-3683
Popis:	To characterize optic disc parameters, retinal nerve fiber layer thickness (RNFLT), and the intraocular pressure (IOP) of myopic children under continual topical 0.25% atropine treatment.From October 1, 2010 to September 31, 2011, 67 eyes of 35 myopic children were recruited. The children were treated with 0.25% atropine nightly for myopia control. Visual acuity, refraction, IOP, axial length (AL, IOL Master), RNFLT, and optic disc parameters (Stratus OCT) were measured at enrollment and every 2 months. All patients had at least 1 year of follow-up.Enrolled children had a mean age of 10.3 ± 2.4 years (5-15 years). Of the 67 studied eyes, the mean spherical equivalent (SE) was -2.60 ± 1.58 diopters (D) (-6.75--0.5 D). Under the treatment of 0.25% atropine, myopia increased by 0.53 ± 0.10D per year (P 0.0001), and AL elongated by 0.245 ± 0.042 mm per year (P 0.0001). No significant change was noted in the IOP and optic nerve parameters including peripapillary RNFLT, areas of optic disc, cup and rim, or cup/disc ratio over the follow-up period during atropine treatment (P 0.05).0.25% Atropine treatment for myopia control did not significantly affect the IOP, optic nerve parameters, and RNFLT in children over a mean of 15.2 ± 2.4 months treatment and follow-up. 0.25% Atropine is a relatively safe option for myopia control.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e00262559b5389d32234ac8ce4cb207 https://doi.org/10.1080/02713683.2017.1359846 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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