Can single cell gel electrophoresis [comet assay] predict the outcome in neonatal sepsis?

Autor:	SVishnu Bhatt, Parkash Chand, NA Priyadharshini
Rok vydání:	2018
Předmět:	Gel electrophoresis Histology neonatal sepsis Neonatal sepsis business.industry Cell Medicine (miscellaneous) lcsh:Human anatomy medicine.disease Molecular biology lcsh:QM1-695 Comet assay medicine.anatomical_structure comet assay medicine predictor of outcome Anatomy business
Zdroj:	National Journal of Clinical Anatomy, Vol 7, Iss 3, Pp 153-156 (2018) National Journal of Clinical Anatomy, Vol 7, Iss 03, Pp 153-156 (2018)
ISSN:	2277-4025
DOI:	10.4103/2277-4025.294766
Popis:	Background & aim : Early diagnosis of neonatal sepsis is important for effective management and recovery. The available methods for diagnosis were not useful in predicting outcome. In the present study the technique of single cell gel electrophoresis [comet assay] which measures DNA damage was used to predict the outcome of neonatal sepsis. Material & methods : Comet Assay [single cell gel electrophoresis, SCGE] was used as a tool to assess the DNA damage in 3 5 term neonates with sepsis .The comet parameters were compared between those who recovered and expired due to sepsis neonatorum. Results were analysed using independent student t test with SPSS software version 19. p values
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de2be14952ea044f96f21aff69ea5bb https://doi.org/10.4103/2277-4025.294766 Zobrazit plný text záznamu