Inflammation in nonalcoholic steatohepatitis
| Autor: | Curtis K. Argo, R. Christopher Harmon, Dina Tiniakos |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Male
Nonalcoholic steatohepatitis medicine.medical_specialty Cirrhosis Abdominal Fat Adipokine Inflammation Fructose digestive system Gastroenterology Simple steatosis Hepatitis Mice Adipokines Non-alcoholic Fatty Liver Disease Fibrosis Internal medicine Nonalcoholic fatty liver disease medicine Animals Humans Muscle Skeletal Hepatology business.industry nutritional and metabolic diseases Lipid Metabolism medicine.disease digestive system diseases Fatty Liver Gastrointestinal Tract Oxidative Stress Lipotoxicity Immunology Cytokines Inflammation Mediators Insulin Resistance medicine.symptom business |
| Zdroj: | Expert Review of Gastroenterology & Hepatology. 5:189-200 |
| ISSN: | 1747-4132 1747-4124 |
| Popis: | Nonalcoholic fatty liver disease (NAFLD) describes a range of disorders characterized by excess accumulation of triglyceride within the liver. While simple steatosis may be clinically stable, nonalcoholic steatohepatitis (NASH) can be progressive. Inflammation is believed to be the driving force behind NASH and the progression to fibrosis and subsequent cirrhosis. This article will review and interpret the current literature in an attempt to expand our understanding of the environmental and genetic causes of inflammation and its effects in NAFLD. |
| Databáze: | OpenAIRE |
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