Thoracic ultrasound accuracy for the investigation of initial neonatal respiratory distress
| Autor: | Barthélémy Tosello, Michel Panuel, Laurent Thomachot, C. Nicaise, C. Grimaldi, Véronique Brévaut-Malaty, B. Puech, Fabrice Michel, Sophie Hassid, R. Vialet |
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| Přispěvatelé: | Sol Agro et hydrosystème Spatialisation (SAS), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Saint-Gobain Recherche (SGR), Saint-Gobain, Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de recherche pour le développement [IRD] : UR206-Centre National de la Recherche Scientifique (CNRS), Département de Pédiatrie-Néonatologie, Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital Nord [CHU - APHM], UMR 6578 : Anthropologie Bio-Culturelle (UAABC), Université de la Méditerranée - Aix-Marseille 2-Centre National de la Recherche Scientifique (CNRS), Réanimation Pédiatrique et Néonatale, Centre Hospitalier Universitaire Nord, Aix Marseille Université (AMU), Assistance Publique - Hôpitaux de Marseille (APHM), Anthropologie bio-culturelle, Droit, Ethique et Santé (ADES), Aix Marseille Université (AMU)-EFS ALPES MEDITERRANEE-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Thoracic Context (language use) 03 medical and health sciences 0302 clinical medicine Sensitivity 030225 pediatrics Positive predicative value Meconium aspiration syndrome Medicine Humans Newborn/*diagnostic imaging Pneumomediastinum Prospective Studies Accuracy Ultrasonography Respiratory Distress Syndrome Newborn Respiratory Distress Syndrome [SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics Respiratory distress Thoracic ultrasound business.industry Infant Newborn Infant Reproducibility of Results Gold standard (test) medicine.disease Newborn Radiography Neonatal respiratory distress Pneumothorax Pediatrics Perinatology and Child Health Specificity Radiography Thoracic Female Differential diagnosis business |
| Zdroj: | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2019, 26 (8), pp.459--465. ⟨10.1016/j.arcped.2019.09.009⟩ |
| Popis: | Place: France; Thoracic ultrasound (TUS) is increasingly studied in neonatal respiratory distress but chest x-ray (CXR) remains the first-line exam. We aimed to evaluate its diagnostic performance for the investigation of unselected causes of neonatal respiratory distress in daily practice. We conducted a descriptive, prospective, and single-center diagnostic accuracy study in a tertiary hospital, including term and preterm newborns who needed a CXR because of respiratory conditions occurring at birth or during the first 24h of life. TUS was compared to the reference diagnosis, which was the association between the CXR results, the clinical initial context, and the patient's outcome. Fifty-two newborns were included and 104 hemi-thorax ultrasounds were analyzed. Sensitivity, specificity, positive and negative predictive values (PPV, NPV), diagnosis accuracy, as well as the positive and negative likelihood ratio of TUSs were 100% for respiratory distress syndrome (RDS), transient tachypnea of newborn (TTN), pneumomediastinum, meconium aspiration syndrome, and absence of pulmonary disease. TUS also showed 100% sensitivity and NPV for pneumothorax, but specificity was 97% and PPV was 50%. Kappa concordance between TUS and either CXR alone or the radiological/clinical gold standard was 0.79 and 0.95, respectively. CONCLUSION: TUS at the newborn's bedside is efficient for investigating the main neonatal respiratory diseases, especially for the confirmation of RDS or TTN and for the exclusion of differential diagnosis or complications. |
| Databáze: | OpenAIRE |
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