Tolerability and Clinical Utility of the Bravo pH Capsule in Children
| Autor: | Julia E. Weiss, Brian E. Lacy, Maurice L. Kelley, Susan Edwards, Lisa Paquette, Kim Ornvold |
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| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Abdominal pain Esophageal pH Monitoring animal structures Adolescent Nausea Biopsy Monitoring Ambulatory Gastroenterology Esophagus Internal medicine medicine Humans Child medicine.diagnostic_test Esophageal disease business.industry Reflux Hydrogen-Ion Concentration medicine.disease Treatment Outcome medicine.anatomical_structure Tolerability Child Preschool Gastroesophageal Reflux Vomiting Female Esophagoscopy medicine.symptom Esophageal pH monitoring business |
| Zdroj: | Journal of Clinical Gastroenterology. 43:514-519 |
| ISSN: | 0192-0790 |
| DOI: | 10.1097/mcg.0b013e31818fba38 |
| Popis: | Goals: To prospectively evaluate the tolerability and clinical utility of the Bravo pH capsule in children. Background: Acid reflux is common in children, and pH testing can be used to correlate acid exposure with symptom expression. The tolerability and clinical utility of the Bravo capsule in children has not been prospectively evaluated. Methods: This was a prospective, open-label trial conducted at an academic medical center. Patient demographics, symptoms, and medication use were recorded in an outpatient setting. After Bravo capsule placement, patients were followed to determine whether the results of the Bravo capsule study changed clinical management. Results: Fifty children (mean ± SD = 13 ± 3 y; 52% female) were studied; no complications occurred. Reflux symptoms (40%), abdominal pain (18%), and nausea/vomiting (14%) were the 3 most common symptoms leading to Bravo capsule placement. Nearly all studies (96%) were performed off acid-suppressing medications. Results of the Bravo pH study changed clinical care in 88% of children; management changed more frequently in children with an abnormal study (94%) versus those with a normal study (78%; P < 0.0001). Conclusions: The Bravo pH capsule is a safe, well-tolerated test to evaluate acid reflux symptoms in children, and the data obtained frequently changes patient management. |
| Databáze: | OpenAIRE |
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