Gender differences on effectiveness of a school-based physical activity intervention for reducing cardiometabolic risk: a cluster randomized trial

Autor: Natalia María Arias-Palencia, Jorge Cañete García-Prieto, Sara López-Martínez, Blanca Notario-Pacheco, Montserrat Solera-Martínez, Mairena Sánchez-López, Ricardo Mora-Rodriguez, Coral Torrijos-Niño, Vicente Martínez-Vizcaíno, Fernando Rodríguez-Artalejo, Fernando Salcedo-Aguilar, Pablo Franquelo-Morales
Rok vydání: 2014
Předmět:
Male
Medicine (miscellaneous)
Blood Pressure
Body Mass Index
law.invention
Cohort Studies
Randomized controlled trial
Risk Factors
law
Cluster Analysis
Insulin
Cluster randomised controlled trial
Child
Children
Adiposity
Metabolic Syndrome
Schools
Nutrition and Dietetics
C-Reactive Protein
Treatment Outcome
Adipose Tissue
Cardiovascular Diseases
Female
Waist Circumference
Underweight
medicine.symptom
Cohort study
medicine.medical_specialty
Intervention
Physical Therapy
Sports Therapy and Rehabilitation
Clinical nutrition
Motor Activity
Sex Factors
Environmental health
medicine
Humans
Obesity
Risk factor
Triglycerides
Physical activity
business.industry
Research
Body Weight
Cholesterol
HDL
Cholesterol
LDL
Cardiometabolic risk factors
medicine.disease
Physical therapy
Patient Compliance
Metabolic syndrome
business
Risk Reduction Behavior
Body mass index
Follow-Up Studies
Zdroj: The International Journal of Behavioral Nutrition and Physical Activity
ISSN: 1479-5868
Popis: Background Studies that have examined the impact of a physical activity intervention on cardiometabolic risk factors have yielded conflicting results. The objective of this study was to assess the impact of a standardized physical activity program on adiposity and cardiometabolic risk factors in schoolchildren. Methods Cluster randomized trial study of 712 schoolchildren, 8–10 years, from 20 public schools in the Province of Cuenca, Spain. The intervention (MOVI-2) consisted of play-based and non-competitive activities. MOVI-2 was conducted during two 90-minute sessions on weekdays and one 150-minute session on Saturday mornings every week between September 2010 and May 2011. We measured changes in adiposity (overweight/obesity prevalence, body mass index [BMI], triceps skinfold thickness [TST], body fat %, fat-free mass, waist circumference) and other cardiometabolic risk factors (LDL-cholesterol, triglycerides/HDL-cholesterol ratio, insulin, C-reactive protein and blood pressure). The analyses used mixed regression models to adjust for baseline covariates under cluster randomization. Results Among girls, we found a reduction of adiposity in intervention versus control schools, with a decrease in TST (−1.1 mm; 95% confidence interval [CI] -2.3 to −0.7), body fat % (−0.9%; 95% CI −1.3 to −0.4), waist circumference (−2.7 cm; 95% CI −4.5 to −0.9), and an increase in fat-free mass (0.3 kg; 95% CI 0.01 to 0.6). The intervention also led to lower serum LDL-cholesterol and insulin levels. Among boys, a reduction in waist circumference (−1.4 cm; 95% CI −2.6 to −0.1; P = 0.03), and an increase in fat-free mass (0.5 kg; 95% CI 0.2 to 0.9; P = 0.003) was associated with the intervention versus control schools. The prevalence of overweight/obesity or underweight, BMI, and other cardiometabolic risk factors was not modified by the intervention. No important adverse events were registered. Conclusions An extracurricular intervention of non-competitive physical activity during an academic year, targeting all schoolchildren regardless of body weight, is a safe and effective measure to reduce adiposity in both genders and to improve cardiometabolic risk profile in girls. Trial registration Clinical trials NCT01277224. Electronic supplementary material The online version of this article (doi:10.1186/s12966-014-0154-4) contains supplementary material, which is available to authorized users.
Databáze: OpenAIRE
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