Rasmussen syndrome in a tropical environment: a study of six (6) observations
| Autor: | Diallo Mamadou Saliou, Sakadi Foksouna, Camara Doussou, Rafkat Said Abdallah, Bah Fatimatou Korka, Diallo Souleymane Mbara, Barry Souleymane Djigué, Diakité Mamady, Konaté Mamady, Sakho Aminata, Millimono Victorine, Cisse Amara, Soumah Fodé Mohamed, Carlos Othon Guelngar, Konaté Mahadi, Sanni Yaya Aminou, Condé Salematou, Djibo Hamani Bachir Abdoul, Douna Granga Daouya, Barry Mamadou Ciré, Kassa Dago François, Cisse Fode Abass, Djibo Hassane Fatimata, Diallo Mohamed Tafsir, Camara Naby, Touré Mohamed Lamine |
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| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty Rasmussen syndrome Neurology Neurosciences. Biological psychiatry. Neuropsychiatry Disease Medicine SSA Valproic Acid Epilepsy business.industry Hemiatrophy General Neuroscience Carbamazepine medicine.disease Psychiatry and Mental health Chronic encephalitis Etiology Surgery Neurology (clinical) Neurosurgery Pshychiatric Mental Health business Encephalitis RC321-571 medicine.drug |
| Zdroj: | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, Vol 57, Iss 1, Pp 1-8 (2021) |
| ISSN: | 1687-8329 |
| DOI: | 10.1186/s41983-021-00409-x |
| Popis: | Background In sub-Saharan Africa, encephalitis of various etiologies is a major public health problem and Rasmussen syndrome is rarely diagnosed due to under-medicalization. The objective of this study is to describe the clinical and neuroradiological forms, especially since this affection is little known in sub-Saharan Africa as evidenced by the scarcity of publications. Results A retrospective, descriptive and analytical study of six (6) cases of Rasmussen syndrome, shows that it is an unrecognized disease in Africa. Men were more represented with a frequency of 67% with a young age. The clinical picture dominated by 100% seizures, mental deterioration and hemiparesis. The etiology is still questionable, probably autoimmune in our study. Conclusion Rasmussen syndrome accounts for 3% in 219 patients hospitalized for epileptic conditions. This study shows a clinical profile dominated by recurrent epileptic seizures refractory to the drugs Phenobarbital, Valproic Acid and Carbamazepine, the only antiepileptics available in the country. These results are valid for therapeutic and prognostic discussion. |
| Databáze: | OpenAIRE |
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