Ultrastructural changes in osteocytes in microgravity conditions
Autor: | V.S. Oganov, N.V. Zolotova, N.V. Rodionova |
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Rok vydání: | 2003 |
Předmět: |
Atmospheric Science
Acid Phosphatase Aerospace Engineering Bone Matrix Golgi Apparatus Bone tissue Iliac crest Osteocytes law.invention Ilium Calcification Physiologic law medicine Animals Process (anatomy) Organelles Osteoblasts Chemistry Weightlessness Astronomy and Astrophysics Histology Osteoblast Space Flight Adaptation Physiological Macaca mulatta Cell biology Microscopy Electron Geophysics medicine.anatomical_structure Space and Planetary Science Osteocyte Ultrastructure General Earth and Planetary Sciences Bone Remodeling Collagen Electron microscope Lysosomes |
Zdroj: | Advances in space research : the official journal of the Committee on Space Research (COSPAR). 30(4) |
ISSN: | 0273-1177 |
Popis: | We examined the histology and morphometry of biosamples (biopsies) of the iliac crest of monkeys, flown 14 days aboard the “Bion-11”, using electron microscopy. We found, that some young osteocytes take part in the activization of collagen protein biosynthesis in the adaptive remodeling process of the bone tissue to microgravity conditions. Osteocyte lacunae filled with collagen fibrils; this correlates with fibrotic osteoblast reorganization in such zones. The osteolytic activity in mature osteocytes is intensified. As a result of osteocyte destruction, the quantity of empty osteocytic lacunae in the bone tissue increases. |
Databáze: | OpenAIRE |
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