Ultrastructural changes in osteocytes in microgravity conditions

Autor: V.S. Oganov, N.V. Zolotova, N.V. Rodionova
Rok vydání: 2003
Předmět:
Zdroj: Advances in space research : the official journal of the Committee on Space Research (COSPAR). 30(4)
ISSN: 0273-1177
Popis: We examined the histology and morphometry of biosamples (biopsies) of the iliac crest of monkeys, flown 14 days aboard the “Bion-11”, using electron microscopy. We found, that some young osteocytes take part in the activization of collagen protein biosynthesis in the adaptive remodeling process of the bone tissue to microgravity conditions. Osteocyte lacunae filled with collagen fibrils; this correlates with fibrotic osteoblast reorganization in such zones. The osteolytic activity in mature osteocytes is intensified. As a result of osteocyte destruction, the quantity of empty osteocytic lacunae in the bone tissue increases.
Databáze: OpenAIRE