The vessels within epithelial circle (VEC) pattern as visualized by magnifying endoscopy with narrow-band imaging (ME-NBI) is a useful marker for the diagnosis of papillary adenocarcinoma: a case-controlled study
| Autor: | Toshiyuki Matsui, Atsuko Ota, Takashi Nagahama, Takao Kanemitsu, Shoko Fujiwara, Kenshi Yao, Yu Matsushima, Hiroshi Tanabe, Yasuhiro Takaki, Akinori Iwashita, Yoichiro Ono |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Cancer Research Pathology medicine.medical_specialty Narrow Band Imaging Papillary adenocarcinoma Surgical oncology Stomach Neoplasms Gastroscopy Preoperative Care Carcinoma Medicine Humans Neoplasm Invasiveness Pathological Aged Retrospective Studies Aged 80 and over medicine.diagnostic_test business.industry Incidence (epidemiology) Gastroenterology General Medicine Middle Aged medicine.disease Endoscopy Adenocarcinoma Papillary Oncology Gastric Mucosa Case-Control Studies Tubular Adenocarcinoma Adenocarcinoma Female business |
| Zdroj: | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 17(3) |
| ISSN: | 1436-3305 |
| Popis: | Pathological studies indicate papillary adenocarcinomas are more aggressive than tubular adenocarcinomas, but a definitive diagnosis is difficult using conventional endoscopy alone. The vessels within an epithelial circle (VEC) pattern, visualized using magnifying endoscopy with narrow-band imaging (ME-NBI), may be a feature of papillary adenocarcinoma. The aims of our study were to investigate whether the VEC pattern is useful in the preoperative diagnosis of papillary adenocarcinoma and to determine whether VEC-positive adenocarcinomas are more malignant than VEC-negative lesions. From 395 consecutive early gastric cancers resected using the endoscopic submucosal dissection method, we analyzed 35 VEC-positive lesions and 70 VEC-negative control lesions matched for size and macroscopic type. We evaluated (1) the correlation between the incidence of VEC-positive cancers and the histological papillary structure and (2) differences in the incidence of coexisting undifferentiated carcinoma in VEC-positive and VEC-negative cancers and the incidence of submucosal and vascular invasion. Histological papillary structure was seen in 94 % (33/35) of VEC-positive and 9 % (6/70) of VEC-negative cancers, a significant difference (P |
| Databáze: | OpenAIRE |
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