Factors associated with low cognitive performance in general practice

Autor: Daniel Mayeux, François Kohler, Bruno Sauron, François Piette, Marie-José Dealberto, Serge Lubin, Annick Alpérovitch, Christian Derouesné, P. Boyer
Rok vydání: 1994
Předmět:
Zdroj: European Archives of Psychiatry and Clinical Neuroscience. 244:53-58
ISSN: 1433-8491
0940-1334
DOI: 10.1007/bf02193519
Popis: In the preparatory phase of a randomised controlled trial data were collected to assess the magnitude of changes on cognitive functions in 1628 volunteers (age range 45-75 years) that were recruited from general practitioners' patient population. Subjects were administered a short neuropsychological battery of tests including three paper-and-pencil tests, which assessed immediate recall, delayed memory, and attention. Being on antihypertensive medication was associated with low results for all three tests in every age group, and in all strata according to blood pressure levels. Psychotropic drug use was correlated with low results for all three tests. Differences between psychotropic drug users and nonusers increased with age. Antihypertensive treatment and psychotropic drug use seem to be important to consider in longitudinal studies of cognitive decline in aging.
Databáze: OpenAIRE