Sinuclean Nebules treatment in children suffering from otitis media with effusion
| Autor: | A Varricchio, Vincenzo Pastore, Giorgio Ciprandi, Nicola Mansi, A. Della Volpe, A De Lucia, Alfonso Maria Varricchio |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Evening Group A Group B 03 medical and health sciences 0302 clinical medicine Audiometry Double-Blind Method 030225 pediatrics otorhinolaryngologic diseases Medicine Humans 030223 otorhinolaryngology Child Therapeutic Irrigation Administration Intranasal Morning medicine.diagnostic_test business.industry Otitis Media with Effusion Plant Extracts Hearing Tests Nebulizers and Vaporizers General Medicine Cucurbitacins Cucurbitaceae Otitis medicine.anatomical_structure Otorhinolaryngology Effusion Anesthesia Child Preschool Pediatrics Perinatology and Child Health Middle ear Female medicine.symptom business |
| Zdroj: | International journal of pediatric otorhinolaryngology. 94 |
| ISSN: | 1872-8464 |
| Popis: | Objective Otitis media with effusion (OME) is an ear disorder defined by the presence of fluid in the middle ear without signs or symptoms of acute infection. The current randomized, double-blind, controlled study aimed to evaluate whether Sinuclean Nebules treatment, administered by nasal douche (Rinowash), could induce ear healing better than isotonic saline in children with OME. Methods The study was randomized, double-blind, and controlled. Group A (30 children) was treated with Sinuclean Nebules 45 and Group B (31 children) was treated with isotonic saline; both compounds were administered by nasal nebulization with Rinowash nasal douche twice/day in the morning and in the evening for 10 days, followed by a one-week suspension, and after by a second course as the first. Tympanogram and audiometry were performed at baseline and after treatment. Results Considering the global evaluation of the treatment: in Group A, 28 (93.3%) patients had complete resolution and 2 (6.7%) had partial resolution; in Group B, all patients had failure of treatment. There was a significant difference between groups (p Conclusion The current randomized-controlled study demonstrated that Sinuclean Nebules was effective and in the treatment of children with OME. |
| Databáze: | OpenAIRE |
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