Lack of Transplacental Infection with Scrub Typhus Organisms in Laboratory Mice *
| Autor: | A. Shirai, Elsie Gan, Michael G. Groves, Teik Chye Chan |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Placenta
Avirulent strain Virulence Physiology Scrub typhus Mice Fetus Pregnancy Virology medicine Animals Pregnancy Complications Infectious Maternal-Fetal Exchange reproductive and urinary physiology biology Inoculation Brain Transplacental Fetal Blood bacterial infections and mycoses medicine.disease biology.organism_classification Antibodies Bacterial Orientia tsutsugamushi Infectious Diseases Rickettsia Liver Scrub Typhus biology.protein Female Parasitology Antibody Spleen |
| Zdroj: | The American Journal of Tropical Medicine and Hygiene. 33:285-287 |
| ISSN: | 1476-1645 0002-9637 |
| DOI: | 10.4269/ajtmh.1984.33.285 |
| Popis: | Female mice were inoculated with either a virulent or avirulent strain of Rickettsia tsutsugamushi before (1 month and 1 week) or after (approximately 10 days) impregnation. From each group, two pregnant mothers were killed on day 20 post-impregnation, and fetuses and placentas were examined for rickettsiae. Organisms were isolated from 80% of placentas but not from the fetuses. Immediately following parturition, litters from 50% of the infected mothers were exchanged with litters from uninfected mothers. In all cases, no scrub typhus rickettsiae were found in the litters examined on days 1, 7, and 30 postpartum, and no antibody was found in sera collected 1 and 2 months postpartum. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|