Prevalence of Osteoporosis in Ambulatory Postmenopausal Women from A Semiurban Region in Southern India: Relationship to Calcium Nutrition and Vitamin D Status
| Autor: | Nihal Thomas, Thomas V Paul, Regi Oommen, Mandalam S. Seshadri, Narayana V. Mahendri, Arun Jose |
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| Rok vydání: | 2008 |
| Předmět: |
Vitamin
medicine.medical_specialty Bone density Endocrinology Diabetes and Metabolism Osteoporosis India chemistry.chemical_compound Absorptiometry Photon Endocrinology Bone Density Internal medicine Vitamin D and neurology Humans Medicine Vitamin D Osteoporosis Postmenopausal Aged Femoral neck Aged 80 and over business.industry General Medicine Middle Aged medicine.disease Calcium Dietary medicine.anatomical_structure chemistry Ambulatory Cohort Physical therapy Female business Body mass index |
| Zdroj: | Endocrine Practice. 14:665-671 |
| ISSN: | 1530-891X |
| DOI: | 10.4158/ep.14.6.665 |
| Popis: | Objective: To assess the prevalence of osteoporosis in healthy ambulatory postmenopausal Indian women as measured by dual-energy x-ray absorptiometry and to study the dietary calcium intake and vitamin D status and their influence on bone mineral density (BMD). Methods: We conducted a community-based crosssectional study in a semiurban region. A randomized clus ter sampling technique was used. The study cohort consisted of 150 ambulatory postmenopausal women ( ≥50 years old). Dual-energy x-ray absorptiometry for BMD was performed at the lumbar spine and femoral neck. Dietary calcium intake and biochemical variables were assessed. Results: The prevalence of osteoporosis was 48% at the lumbar spine, 16.7% at the femoral neck, and 50% at any site. The mean dietary calcium intake was much lower than the recommended intake for this age-group. There was a significant positive correlation between body mass index and BMD at the lumbar spine and the femoral neck (r = 0.4; P = .0001). BMD at the femoral neck was signif icantly less (mean, 0.657 versus 0.694 g/cm 2) in the vita min D-insufficient study subjects in comparison with the vitamin D-sufficient women ( P = .03). Conclusion: The high prevalence of osteoporosis and vitamin D insufficiency in this semiurban group of post menopausal women in India is a major health concern. Measures such as adequate calcium intake and vitamin D supplementation in women of this age-group may be ben eficial.(EndocrPract.2008;14:665-671) |
| Databáze: | OpenAIRE |
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