The Path of Most Resistance: A Rare Instance of Metastatic Pancreatic Adenocarcinoma Identified Within Skeletal Muscle
| Autor: | S. Lamsal, Travis Meyer, Taylor S Harmon, Caitlin E. Harmon, Khaled Mohamed |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pathology
medicine.medical_specialty Palliative care positron emission tomography medicine.medical_treatment 030204 cardiovascular system & hematology core needle biopsy Metastasis 03 medical and health sciences 0302 clinical medicine Carcinoembryonic antigen interventional radiology medicine pancreatic adenocarcinoma biology business.industry carcinoembryonic antigen General Engineering Skeletal muscle computed tomography desmoplastic microenvironment Metastatic Pancreatic Adenocarcinoma medicine.disease carbohydrate antigen 19-9 Primary tumor skeletal muscle metastasis whipple procedure Radiation therapy medicine.anatomical_structure Oncology biology.protein Adenocarcinoma business Radiology 030217 neurology & neurosurgery |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Soft tissue neoplastic metastases, specifically to the skeletal muscle, are uncommon in comparison to metastases within the abdomen, thorax, or intracranial regions. Specifically, pancreatic adenocarcinoma with skeletal muscle metastasis is a rare clinical phenomenon and is hardly reported. There is a high mortality rate after the diagnosis of metastatic pancreatic adenocarcinoma, attributed to inadequate screening and advanced staging upon incidental discovery. Rarely, metastatic lesions manifest in the skeletal muscle and are hardly documented. Some of the factors that deter skeletal muscle tumor implantation include the deficiency of skeletal muscle mediators and genetic makeup of the primary tumor. Surgical resection of pancreatic adenocarcinoma with adjuvant chemotherapy demonstrates the best prognosis; however, surgical management is usually limited to patients without known metastatic disease. Alternative treatment options such as chemotherapy and radiotherapy are used in the palliative care setting. Here, we present the case of a patient with previously diagnosed and treated pancreatic adenocarcinoma in remission, with biopsy-proven metastases isolated within the skeletal muscle. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|