Ecological niche modelling of Hemipteran insects in Cameroon ; the paradox of a vector-borne transmission for Mycobacterium ulcerans, the causative agent of Buruli ulcer

Autor: Daniel Sanhueza, Andres Garchitorena, Kevin Carolan, Laurent Marsollier, Philippe Le Gall, Danny Lo Seen, Gaëtan Texier, Solange Meyin A. Ebong, Jean-François Guégan, Jordi Landier
Přispěvatelé: Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Université de Yaoundé I, Shoklo Malaria Research Unit [Mae Sot, Thailand] (SMRU), Mahidol Oxford Tropical Medicine Research Unit (MORU), University of Oxford-Mahidol University [Bangkok]-Wellcome Trust-University of Oxford-Mahidol University [Bangkok]-Wellcome Trust, ATOMycA (CRCINA-ÉQUIPE 6), Centre de Recherche en Cancérologie et Immunologie Nantes-Angers (CRCINA), Université d'Angers (UA)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Université d'Angers (UA)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre hospitalier universitaire de Nantes (CHU Nantes), Wellcome Trust-Mahidol University [Bangkok]-University of Oxford [Oxford]-Wellcome Trust-Mahidol University [Bangkok]-University of Oxford [Oxford], Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Centre National de la Recherche Scientifique (CNRS)-Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Centre National de la Recherche Scientifique (CNRS)-Université d'Angers (UA)
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Buruli ulcer
Maladie de la peau
Environmentally-acquired disease
Business
Management and Accounting(all)
Geographic Mapping
L73 - Maladies des animaux
law.invention
0302 clinical medicine
law
Abundance (ecology)
Dynamique des populations
Cameroon
skin and connective tissue diseases
Buruli Ulcer
ComputingMilieux_MISCELLANEOUS
2. Zero hunger
[SDV.EE]Life Sciences [q-bio]/Ecology
environment
0303 health sciences
Naucoridae
Ecological niche modelling
biology
Ecology
Facteur du milieu
Belostomatidae
Transmission (mechanics)
Vecteur de maladie
Mycobacterium ulcerans
Habitat suitability
L20 - Écologie animale
L72 - Organismes nuisibles des animaux
Computer Science(all)
General Computer Science
Biotope
Vector-borne transmission
030231 tropical medicine
Context (language use)
Mycobacterium
Hemiptera
Heteroptera
03 medical and health sciences
Maladie de l'homme
Insecte aquatique
medicine
Animals
Humans
Spatial distribution
Modélisation environnementale
Ecosystem
Transmission des maladies
030304 developmental biology
Ecological niche
Research
Public Health
Environmental and Occupational Health
Distribution spatiale
biology.organism_classification
medicine.disease
General Business
Management and Accounting
[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology
Insect Vectors
Zdroj: International Journal of Health Geographics
International Journal of Health Geographics, 2014, 13 (1), ⟨10.1186/1476-072X-13-44⟩
International Journal of Health Geographics, BioMed Central, 2014, 13 (1), ⟨10.1186/1476-072X-13-44⟩
ISSN: 1476-072X
DOI: 10.1186/1476-072X-13-44⟩
Popis: Background: The mode of transmission of the emerging neglected disease Buruli ulcer is unknown. Several potential transmission pathways have been proposed, such as amoebae, or transmission through food webs. Several lines of evidence have suggested that biting aquatic insects, Naucoridae and Belostomatidae, may act as vectors, however this proposal remains controversial. Materials and methods: Herein, based on sampling in Cameroon, we construct an ecological niche model of these insects to describe their spatial distribution. We predict their distribution across West Africa, describe important environmental drivers of their abundance, and examine the correlation between their abundance and Buruli ulcer prevalence in the context of the Bradford-Hill guidelines. Results: We find a significant positive correlation between the abundance of the insects and the prevalence of Buruli ulcer. This correlation changes in space and time, it is significant in one Camerounese study region in (Akonolinga) and not other (Bankim). We discuss notable environmental differences between these regions. Conclusion: We interpret the presence of, and change in, this correlation as evidence (though not proof) that these insects may be locally important in the environmental persistence, or transmission, of Mycobacterium. ulcerans. This is consistent with the idea of M. ulcerans as a pathogen transmitted by multiple modes of infection, the importance of any one pathway changing from region to region, depending on the local environmental conditions.
Databáze: OpenAIRE
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