Incidence, predictors and clinical outcomes of residual stenosis after aortic valve-in-valve
| Autor: | Ran Kornowski, Massimo Napodano, Mauricio G. Cohen, Alfredo Giuseppe Cerillo, Sabine Bleiziffer, Stephan Windecker, Tara L. Jones, Eric Horlick, Ankur Kalra, Magdalena Erlebach, Lukas Capek, Vasco Gama Ribeiro, Santiago Garcia, Michael J. Reardon, Sami Alnasser, David Holzhey, Didier Champagnac, Tobias Zeus, Adnan K. Chhatriwalla, Nicolas M. Van Mieghem, Raffi Bekeredjian, Jan Malte Sinning, Isaac George, Rüdiger Lange, Christian J. Rustenbach, Petur Petursson, Matheus Simonato, Enrico Ferrari, Joachim Schofer, Nikolaos Bonaros, John G. Webb, Danny Dvir, Giselle A. Baquero, Philippe Pibarot |
|---|---|
| Přispěvatelé: | Cardiology |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
Reoperation Aortic valve medicine.medical_specialty Hemodynamics 030204 cardiovascular system & hematology Prosthesis Design Risk Assessment Body Mass Index Transcatheter Aortic Valve Replacement 03 medical and health sciences Postoperative Complications 0302 clinical medicine Predictive Value of Tests Risk Factors Internal medicine Outcome Assessment Health Care Humans Medicine 030212 general & internal medicine Adverse effect 610 Medicine & health Aged Aged 80 and over Bioprosthesis business.industry Effective orifice area Incidence Incidence (epidemiology) valvular heart disease Aortic Valve Stenosis Residual stenosis medicine.disease Prosthesis Failure medicine.anatomical_structure Echocardiography Aortic Valve Heart Valve Prosthesis Cardiology Female Cardiology and Cardiovascular Medicine business Body mass index |
| Zdroj: | Heart, 104(10), 828-834. BMJ Publishing Group |
| ISSN: | 1355-6037 |
| DOI: | 10.7892/boris.125246 |
| Popis: | ObjectiveWe aimed to analyse the incidence of prosthesis–patient mismatch (PPM) and elevated gradients after aortic valve in valve (ViV), and to evaluate predictors and associations with clinical outcomes of this adverse event.MethodsA total of 910 aortic ViV patients were investigated. Elevated residual gradients were defined as ≥20 mm Hg. PPM was identified based on the indexed effective orifice area (EOA), measured by echocardiography, and patient body mass index (BMI). Moderate and severe PPM (cases) were defined by European Association of Cardiovascular Imaging (EACVI) criteria and compared with patients without PPM (controls).ResultsModerate or greater PPM was found in 61% of the patients, and severe in 24.6%. Elevated residual gradients were found in 27.9%. Independent risk factors for the occurrence of lower indexed EOA and therefore severe PPM were higher gradients of the failed bioprosthesis at baseline (unstandardised beta −0.023; 95% CI −0.032 to –0.014; PConclusionsSevere PPM and elevated gradients after aortic ViV are very common but were not associated with short-term survival and clinical outcomes. The long-term effect of poor post-ViV haemodynamics on clinical outcomes requires further evaluation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|