Effect of serving size and addition of sugar on the glycemic response elicited by oatmeal: A randomized, cross-over study
| Autor: | Susan E Spruill, YiFang Chu, Alexandra L Jenkins, Laura Harkness, B. Jan-Willem van Klinken, Thomas M.S. Wolever |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Adult Blood Glucose Male Sucrose beta-Glucans Adolescent Avena Endocrinology Diabetes and Metabolism Serving Size Beta-glucan 03 medical and health sciences chemistry.chemical_compound Young Adult Animal science Serving size Dietary Carbohydrates Medicine Humans Sugar Rice cereal Glycemic Aged Breakfast Probability 030109 nutrition & dietetics Nutrition and Dietetics Cross-Over Studies business.industry Area under the curve food and beverages Oryza Middle Aged Postprandial Period Crossover study Diet Postprandial Biochemistry chemistry Glycemic Index Area Under Curve Female business Edible Grain Sugars |
| Zdroj: | Clinical nutrition ESPEN. 16 |
| ISSN: | 2405-4577 |
| Popis: | Summary Background & aims We aimed to determine the impact of serving size and addition of sucrose on the glycemic response elicited by oatmeal. Methods We studied 38 healthy subjects (mean ± SD age 40 ± 12 yr, BMI 26.4 ± 3.6 kg/m 2 ) on 8 separate days using a randomized, cross-over design. Capillary blood-glucose responses over 2hr after consuming 30, 40 and 60 g Classic Quaker Quick Oats (18, 24 and 36 g available-carbohydrate [avCHO], respectively) and 30 g Oats plus 9 g sucrose (27 g avCHO) were compared with those after avCHO-matched servings of Cream of Rice cereal (Control) (22, 29, 44 and 33 g cereal, respectively). Blood-glucose incremental area under the curve (iAUC), peak-rise, rate-of-decline, time-to-peak and time-to-baseline were calculated. Results As serving size increased, iAUC, peak-rise, rate-of-decline and time-to-baseline increased significantly for both cereals, but the rate of increase was significantly greater for Control than for Oats. Time-to-peak increased significantly with serving size only for Oats. Compared to avCHO-matched servings of Control, mean (95%CI) iAUC, peak-rise and rate-of-decline, respectively were 22 (16, 27)%, 22 (19, 26)% and 23 (18, 27)% lower after consuming Oats without sucrose and 26 (18, 34)%, 14 (9, 20)% and 16 (9, 24)% lower after consuming Oats plus sucrose. Conclusions Oatmeal elicited a significantly lower glycemic response than avCHO-matched servings of Cream of Rice, even when sucrose was added to the oatmeal. Measures of glycemic response tended to increase with increased serving size; although the pattern of change varied between cereal types. These results suggest that oatmeal may be a good choice for minimizing postprandial glycemia. Clinical trial registry ClinicalTrials.gov ( NCT02506972 ). |
| Databáze: | OpenAIRE |
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